Radio-pathological correlation of a retroperitoneal teratoma in a 2-year-old girl: a case report (original) (raw)

Retroperitoneal Teratoma in an InfantCase Report

Annals of Pathology and Laboratory Medicine, 2019

Common location of teratomas in children are sacrococcygeal, gonadal, mediastinal and retroperitoneal, but teratomas may also occur at very unusual locations. A one-year-old girl presented with a large swelling at her left abdomen. Clinical examination revealed a solitary, non-tender, soft to firm, irregular cystic mass, occupying her left abdominal region. Computed Tomography (CT) scan finding was consistent with retroperitoneal teratoma. Complete surgical excision of the tumour was done without any difficulties. Histology of the excised tumour was conclusive of mature cystic teratoma.

Retroperitoneal Teratoma in Infancy; Report of an Unusual Entity

Journal of Medical Diagnostic Methods, 2017

Primary retroperitoneal teratoma in infancy is extremely rare. In children, it accounts for 3.5-4% of all germ cell tumours and 1-11% of primary retroperitoneal neoplasms. Clinical presentation is often asymptomatic or may present as a palpable mass or abdominal distension. The imaging findings of teratoma are characteristic. Early diagnosis is important for prompt surgical resection. We present a case of huge retroperitoneal teratoma in a 5month-old child presenting with abdominal swelling where computed tomography findings are distinctive. Biopsy led to the definitive diagnosis of mature cystic teratoma of retroperitoneum.

Retroperitoneal teratomas in infancy and childhood

Pediatric Surgery International, 2005

Retroperitoneal teratoma poses a significant problem in the differential diagnosis of Wilms' tumor, neuroblastoma, and other intraabdominal tumors. In an attempt to establish the best diagnostic and treatment modality, we reviewed our experience with retroperitoneal teratomas at a single institution in a 5-year period. Between January 1998 and December 2002, retroperitoneal teratomas were identified in 10 patients, seven females and three males, ranging from age 4 days to 12 years, with seven patients under the age of 1 year. The presence of calcifications or bony structure within the tumor was revealed on abdominal ultrasound study or computed tomography in nine of the 10 lesions. Total excision was performed in nine patients; another patient with grade III immature teratoma received postoperative chemotherapy besides excision. One patient with grade III immature teratoma who did not receive postoperative chemotherapy had a local recurrence 6 months later and was treated by repeated surgical excision and postoperative chemotherapy. All of these patients were free of disease at 8 months to 5 years of follow-up. Retroperitoneal teratomas were usually noted in patients under the age of 1 year. Though large, they are mostly benign lesions with no apparent connection to the retroperitoneal organs and are amenable to curative excision, but histologic evidence of grade III immature teratoma or malignancy demands aggressive postoperative chemotherapy to prevent local recurrence.

Retroperitoneal Teratoma in an Infant

Retroperitoneal teratoma in infancy is exceedingly rare. Progressive enlargement of the abdomen and the presence of an intra-abdominal mass is the most common clinical feature. They constitute third most frequent type of retroperitoneal neoplasm seen in infant and children after Wilm's tumor and neuroblastoma. We report here a case of giant retroperitoneal teratoma in an infant. A 5 month old female child was admitted with complain of abdominal distension. Abdominal CT scan revealed a tumor suggestive of retroperitoneal teratoma. Intraoperative finding revealed that tumor was compressing the atrophic right kidney. Resection of tumor with right nephrectomy was done successfully.

Retroperitoneal teratomas in children

The Indian Journal of Pediatrics, 2006

Objective : This paper aims to highlight the clinical features, investigations and treatment of retroperitoneal teratomas condition. Methods : 12 patients (8 females and 4 males, age range-2 months to 14 yrs) of retroperitoneal teratoma admitted to the department of Pediatric Surgery, King George Medical University, Lucknow between 1980 and 2004 were studied. Investigations included hematology, plain X-ray of the abdomen, intravenous urography, ultrasound, computerised tomography (CT) of the abdomen (after 1990, 8 patients), and serum alpha-fetoprotein assay (after 1991, 6 patients, preoperatively). All patients underwent surgery. Serum alpha-fetoprotein assay was used during follow-up to detect recurrence. Results : Majority of the tumors were left pararenal in location. In two patients there was bilateral involvement. In all except one, the tumor could be excised easily preserving the kidneys. In one child with a massive cystic tumor with bilateral involvement, the tumor was marsupialised in the first stage and excised subsequently. One child died postoperatively, the other 11 children are well and there has been no tumor recurrence on follow-up. Conclusions : Retroperitoneal teratomas are uncommon lesions in children mostly arising in close relation to the kidneys. The majority are benign but complete excision is necessary for cure. Even large tumors with bilateral involvement of the retroperitoneum can be excised while preserving adjacent organs. Serum alphafetoprotein assay is a reliable method of detecting recurrence. [Indian J Pediatr 2006; 73 (3) : 221-223]

Congenital Immature Teratoma of the Retroperitoneum

Journal of Neonatal Surgery

Congenital teratomas occur in extragonadal locations, the commonest site being the sacrococcygeal region. This report describes a rare case of antenatally detected, large, immature retroperitoneal teratoma. The diagnostic and therapeutic challenges of dealing with such a case have been discussed and the relevant literature reviewed. The recurrence of the tumour after gross surgical removal indicates a definitive role of administering chemotherapy in such a case.

Primary Retroperitoneal Teratoma in a Young Male: A Case Report

Cureus, 2021

Primary retroperitoneal teratomas are rare non-seminomatous germ cell tumors that arise from embryonal tissues. They form only 5%-10% of all retroperitoneal tumors. These are usually asymptomatic or present as lump or mass with compressive symptoms. Most of the patients are diagnosed by characteristic computed tomography findings. The chances of malignant transformation are rare. Complete surgical resection is the definitive treatment for most patients. We had a 19 years old young man, presented with pain abdomen and awareness of a lump in the right upper abdomen. Contrast-enhanced computed tomography (CECT) of the abdomen revealed a heterogeneous soft tissue mass in the retroperitoneum with calcification. He was successfully treated with en-bloc complete surgical resection. Histopathology confirmed benign mature teratoma including all three germ layers. The patient is doing fine at nine months of follow-up and planned for CECT abdomen. Primary mature teratomas arise in the retroper...

Retroperitoneal teratomas—potential for surgical misadventure

Journal of Pediatric Surgery, 2008

Background: Retroperitoneal teratoma (RPT) is a relatively uncommon tumor in children. This study concerns 6 children with RPT that involved surrounding structures and required rather extensive operative procedures to successfully excise the lesions. Methods: A review of RPT in children encountered at a single institution over an 8-year period by a single surgeon was carried out. Age at presentation, sex, operative findings, surgical management, and outcomes were evaluated. Results: Four of the 6 patients were girls, and 5 were younger than 6 months at diagnosis. All of the tumors enveloped and displaced the aorta and vena cava, 1 involved the stomach wall, 2 others displaced the renal vessels, and 1 the portal vein. Extensive resection including major vessel ligation was necessary for complete excision. All the tumors were benign, but 1 recurred. There were no deaths; however, 2 children have persistent hypertension. Conclusions: The operative management of RPTs may be complex and challenging. Despite their benign nature, the lesions can attenuate and surround major vessels, making resection difficult. Ligation of major vessels when necessary is tolerated well and may be required for complete tumor excision.

Giant Primary Retroperitoneal Teratoma: A Case Report

Teratomas are congenital tumors derived fromembryonic tissues that may contain derivatives of all three germ layers(ectoderm,mesoderm and endoderm).Primary retroperitoneal teratomas are rare entities.Here we report a case of 15 yrs old girl with huge abdominal lump extending from epigastrium to the pelvic cavity,covering almost all the abdominal quadrants with mild diffuse pain over whole abdomen. Radiolgical evaluation revealed a retroperitoneal mass displacing pancreas,left kidney and bowel loops,composed of calcifications and solid cystic components.Thetumour was resected through a midline laparotomy and the pathology report confirmed the diagnosis of a mature cystic teratoma with no evidence of malignancy or immature components.Thepost operative recovery was uneventful.