Development of a Pteris vittata L. compound database by widely targeted metabolomics profiling (original) (raw)

Biomedical Chromatography, 2021

Abstract

The objective of this work was the development of a detailed, extensive and reliable database of the metabolomes of P. vittata. Using an UPLC-QqQ-MS/MS system and based on the knowledge of retention time and mass spectral characteristics of an in-house collection of authentic standards, we screened for the presence of a large collection of natural compounds. The database represents 359 authenticated metabolites, comprising 220 primary and 139 secondary metabolites (70 flavonoids, 16 phenylpropanoic acid derivatives, 5 coumarins, 2 stilbenoids, 14 benzoic acids, 9 phenols, 20 alkaloids and 3 terpenoids). Comparison of the accumulation of these compounds in two tissues showed that the aerial parts are enriched in flavonols, whereas the subterranean parts were enriched in anthocyanins. The comprehensive database developed here can be highly beneficial in improving the understanding of the chemical basis of plant therapeutic profile by using multivariate analysis, with a particular example of antioxidant activity.

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