Speech disorders in Parkinson’s disease - characteristics, assessment and treatment (original) (raw)
Related papers
Speech dysfunction in early Parkinson's disease
Movement Disorders, 1995
The purpose of this study is to determine if subjects in the early stages of untreated Parkinson's disease (PD) or PD treated with deprenyl alone suffer from motor speech abnormalities. Speech defects are common in advanced PD, including disturbances of respiration, phonation, and articulation. We studied 12 subjects with early PD (Hoehn and Yahr stage s 2 , mean duration disease 3.2 years) who were not taking symptomatic therapy and tested them under two conditions: on and off deprenyl. None of the subjects was depressed or demented (Mini Mental Status mean 29.9/30; Hamilton Depression Rating mean 2.7152). All functioned independently (Schwab and England Activities of Daily Living mean 93.1/100). Acoustic and speech productions were assessed using the DSP Sona-Graph 5500 and an evaluation of dysarthria. All 12 had at least two characteristics of dysarthria on examination, although 8 were not aware of it. Vocal tremor was identified on narrow band spectrogram for four subjects. Deprenyl did not have a consistent effect on speech. Ten subjects had no detectable change in speech on deprenyl, one was worse, and one was improved.
Motor speech disorders in three parkinsonian syndromes: a comparative study
2007
ABSTRACT This paper presents results of an acoustic investigation of speech in progressive supranuclear palsy (PSP), multiple system atrophy (MSA) and idiopathic Parkinson's disease (IPD). The study had two aims:(a) to provide a first acoustic description of the speech of people with PSP and MSA,(b) to compare acoustic characteristics of the dysarthria associated with PSP and MSA with classic hypokinetic dysarthria.
Speech characteristics of parkinson disease
Medical Science and Discovery, 2021
Objective: Parkinson Disease (PD) is known the second most frequent neurodegenerative age-related disorder after Alzheimer’s disease. Although over the six million people worldwide suffer from PD, the main cause of the disease remains are unknown. Speech and language impairments have emerged in most patients with PD during the course of the disease. However, clinical profiles or characteristics that might differentiate individuals with PD who are predisposed to speech and language deficits are generally overlooked. Moreover, factors that expedite language disability have still been remained elusive. It is thought that the awareness of speech and language impairments in PD can significantly help to maintain language abilities as the disease progresses and also may contribute to improving communication skills with patients. For this reason, the present study aims to constitute a comprehensive frame for the speech and language characteristics of individuals with PD
Distinct patterns of speech disorder in early-onset and late-onset de-novo Parkinson’s disease
npj Parkinson's Disease
Substantial variability and severity of dysarthric patterns across Parkinson’s disease (PD) patients may reflect distinct phenotypic differences. We aimed to compare patterns of speech disorder in early-onset PD (EOPD) and late-onset PD (LOPD) in drug-naive patients at early stages of disease. Speech samples were acquired from a total of 96 participants, including two subgroups of 24 de-novo PD patients and two subgroups of 24 age- and sex-matched young and old healthy controls. The EOPD group included patients with age at onset below 51 (mean 42.6, standard deviation 6.1) years and LOPD group patients with age at onset above 69 (mean 73.9, standard deviation 3.0) years. Quantitative acoustic vocal assessment of 10 unique speech dimensions related to respiration, phonation, articulation, prosody, and speech timing was performed. Despite similar perceptual dysarthria severity in both PD subgroups, EOPD showed weaker inspirations (p = 0.03), while LOPD was characterized by decreased v...
Characteristics of speech disfluency in Parkinson disease
Journal of Neurolinguistics, 2010
The purpose of this study was to describe speech disfluency characteristics in a group of 32 individuals with Parkinson disease (PD). Individuals with PD read a standard passage, and percentages of within-word and between-word disfluencies were calculated. The disfluency percentages exhibited by the individuals with PD were significantly greater than age-matched control speakers. Similarity was found between PD-related disfluencies and disfluencies seen in developmental stuttering, as the PD participants produced primarily motoric-based within-word disfluencies, including both repeated movements and fixed postures. A relationship was also found between self-ratings of medication effectiveness and disfluency levels, and this relationship is interpreted relative to the dopamine hypothesis of stuttering. Finally, significant reductions in within-word disfluencies were seen during a clear-speech task, along with an increase in disfluency levels during a monologue compared to a reading task.
Speech Impairment in a Large Sample of Patients with Parkinson’s Disease
Behavioural Neurology, 1999
This study classified speech impairment in 200 patients with Parkinson's disease (PD) into five levels of overall severity and described the corresponding type (voice, articulation, fluency) and extent (rated on a five-point scale) of impairment for each level. From two-minute conversational speech samples, parameters of voice, fluency and articulation were assessed by two trained-raters. Voice was found to be the leading deficit, most frequently affected and impaired to a greater extent than other features in the initial stages. Articulatory and fluency deficits manifested later, articulatory impairment matching voice impairment in frequency and extent at the 'Severe' stage. At the final stage of 'Profound' impairment, articulation was the most frequently impaired feature at the lowest level of performance. This study illustrates the prominence of voice and articulatory speech motor control deficits, and draws parallels with deficits of motor set and motor set instability in skeletal controls of gait and handwriting.
Journal of Neurolinguistics, 2004
One of the frequent signs of Parkinson's disease (PD) is the presence of a progressive hypokinetic dysarthria. Numerous studies have since documented speech motor impairment, but attempts at quantifying any such changes longitudinally throughout the early course of the disease have been rare. In this study, a retrospective analysis of speech was conducted on two well-known individuals with PD and two matched controls to determine if certain acoustic measures were sensitive markers of early pathophysiologic changes or treatment response in PD. Acoustic analyses were conducted on samples of speech produced over a 10-year period surrounding the time of disease diagnosis. Analyses revealed that, for both PD cases, a decrease in fundamental frequency (F 0) variability during free speech was detected prior to clinical diagnosis. Changes in F 0 variability and voice onset time (VOT) were also detected upon the initiation of symptomatic treatment. In a second experiment, an acoustical analysis of speech production was conducted on four newly diagnosed persons with PD and four matched controls, using a standard speech examination protocol. The objective of this follow-up study was to provide corroborating evidence for the results of the first experiment. Analyses revealed that F 0 variability during picture description was diminished in the participants with PD relative to their matched controls. In addition, pause duration was greater in participants
Speech disorders did not correlate with age at onset of Parkinson’s disease
Arquivos de Neuro-Psiquiatria, 2016
Speech disorders are common manifestations of Parkinson´s disease. Objective To compare speech articulation in patients according to age at onset of the disease. Methods Fifty patients was divided into two groups: Group I consisted of 30 patients with age at onset between 40 and 55 years; Group II consisted of 20 patients with age at onset after 65 years. All patients were evaluated based on the Unified Parkinson’s Disease Rating Scale scores, Hoehn and Yahr scale and speech evaluation by perceptual and acoustical analysis. Results There was no statistically significant difference between the two groups regarding neurological involvement and speech characteristics. Correlation analysis indicated differences in speech articulation in relation to staging and axial scores of rigidity and bradykinesia for middle and late-onset. Conclusions Impairment of speech articulation did not correlate with age at onset of disease, but was positively related with disease duration and higher scores ...
Resolving speech disorders in Parkinson disease: our clinical experience with voice therapy
2017
Introduction: Varying degrees of voice and speech disorders may occur in the course of the Parkinson's disease (PD). Lee Silverman Voice Therapy (LSVT) is a specific method which has been developed for these disorders. Materials and Methods: 15 registered Parkinson's patients of our clinic were enrolled in this study. The stage and the symptoms were evaluated by Unified Parkinson's Disease Rating Scale (UPDRS) and the Hoehn and Yahr (H&Y) staging scale. Voice samples were analysed with the comparison of the mean F0 values (Hz) and voice intensity (dB) levels prior to (pre-therapy) and 3 months after (post-therapy) administration the LSVT. Results: Mean age of the patients were 67.2 ± 12.07 (min (44)-max (86)). There was a statistically significant improvement between the pre-therapy and the post-therapy mean Hz and dB levels (p=0.006 and p 0.05). Conclusions: We aimed to improve our understanding of the importance of non-motor symptoms of the PD such as voice and speech ...