Autobiographical Writing Research Papers - Academia.edu (original) (raw)

2025, Updates in Surgery

COVID-19 negatively affected surgical activity, but the potential benefits resulting from adopted measures remain unclear. The aim of this study was to evaluate the change in surgical activity and potential benefit from COVID-19 measures in perspective of Italian surgeons on behalf of SPIGC. A nationwide online survey on surgical practice before, during, and after COVID-19 pandemic was conducted in March–April 2022 (NCT:05323851). Effects of COVID-19 hospital-related measures on surgical patients’ management and personal professional development across surgical specialties were explored. Data on demographics, pre-operative/peri-operative/post-operative management, and professional development were collected. Outcomes were matched with the corresponding volume. Four hundred and seventy-three respondents were included in final analysis across 14 surgical specialties. Since SARS-CoV-2 pandemic, application of telematic consultations (4.1% vs. 21.6%; p < 0.0001) and diagnostic evalua...

2025, Updates in Surgery

2025, Djaimilia Pereira de Almeida: Tecelã de Mundos Passados e Presentes

A obra de Djaimilia Pereira de Almeida já mereceu a atenção de vários académicos quer no âmbito dos estudos literários (Ribeiro, 2019; Sousa, 2017; Torrão, 2017), quer nos estudos de género ou nos estudos pós-coloniais (Brito & Trevisan, 2021; Ferreira, 2021; Khan, 2021; Rendeiro, 2022), visando essencialmente as narra-tivas Esse Cabelo (Almeida, 2015/2018a), Luanda, Lisboa, Paraíso(Almeida, 2018b), Maremoto (Almeida, 2021b) ou As Telefones(Almeida, 2020b).Este capítulo propõe, no âmbito dos estudos de cultura, apresentar a escritora-cronista do seu tempo e do seu lugar, da vida quotidiana da humanidade, num tempo pós-colonial, através das crónicas pu-blicadas em jornais e revistas culturais1 e, posteriormente, compila-das na maioria em Pintado com o Pé (Almeida, 2019). Pretende-se ainda indagar sobre o processo criativo da crónica, ou sobre modos de ver o mundo, que incorpora o uso da imagem, das memórias de anónimos, de lugares, de tempos, de sentidos e senti-mentos. E porque a crónica é o género narrativo que mais se apro-xima da relação entre escrita e vida (Saramago, s.d.), procura-se conhecer a mulher-escritora através das entrevistas que concedeu desde a publicação de Esse Cabelo, em 2015. Por fim, afere-se que as crónicas de Djaimilia Pereira de Almeida, publicadas na imprensa cultural, são um espaço de imaginação, de aprendizagem e experimentação criativa, com liberdade de pensa-mento e expressão, cujos resultados se refletem nos romances por ela publicados.

2025, Pensamento Realidade Revista Do Programa De Estudos Pos Graduados Em Administracao Fea Issn 2237 4418

O desejo humano é a força propulsora da criação: aquilo que os indivíduos desejam determina quem são e o que farão. Melinda Davis inicia seu livro afirmando que sempre desejamos alguma coisa, mas sem saber exatamente o quê, como se aquilo que mais traria satisfação ainda não tivesse sido inventado. Essa ansiedade enigmática que angustia os indivíduos contemporâneos, está atuando no instinto de sobrevivência humana de uma forma inédita ( já que a maior preocupação não mais é a sobrevivência do corpo físico, como veremos adiante ), originando medos e entusiamos que permeiam uma nova cultura do desejo, e consequentemente, do consumo.

2025

Distinction: A Social Critique of the Judgement of Taste (La Distinction: Critique sociale du jugement, 1979) by Pierre Bourdieu, is a sociological report about the state of French culture, based upon the author's empirical research from 1963 until 1968. The English translation was published in 1984, and, in 1998, the International Sociological Association voted Distinction as an important book of sociology published in the 20th century.

2025

Recenze na knihu Oliver Lovrenski: Když nám bylo míň. Z norského originálu Da vi var yngre (2023) přeložil Václav Křenek. 1. vydání. Praha: Paseka, 2024. 248 stran. Vyšlo v časopise Plav 5/2025,... more

2025, Cahiers de civilisation espagnole contemporaine

Resumen : Basado principalmente en la prensa anarquista de los años 1873-1899, este artículo analiza la forma en que se construyó la memoria de los diversos acontecimientos que tuvieron lugar durante los diez meses de la Primera República... more

2025, Via Atlântica

Resenha do romance "Ferry", da escritora portuguesa Djaimilia Pereira de Almeida, lançado pela editora Relógio D'Água, em 2022.

2025, Academia

Just an interesting and respectful story about a homosexual man's life.

2025, Herkünfte erzählen. Verflechtungsästhetiken von Interkulturalität und Intersektionalität in deutschsprachiger Gegenwartsliteratur

Plurale Herkunftserzählungen prägen die gegenwärtige Literatur. Der Plural konterkariert und unterläuft dabei monolithische Konzepte personaler Identität und zeigt die Subjekte als multidimensional verwoben, u.a. in ihren sozialen,... more

2025

Recenze na knihu Kausc, Emma: Narušení děje. Brno: Host 2024.

2025, BRODŇANSKÁ, E., MALINOVSKÁ, Z., ŽIVČÁK, J., 2024. Sv. Gregor z Nazianzu. Verše o sebe. Košice: Equilinia. 452 pp. ISBN 978-80-974749-3-5.

Saint Gregory of Nazianzus. Autobiographical Verses — The period of Late Antiquity is an important milestone in the development of what we now call autobiographical writing. For the first time, a genealogical lineage can be reconstructed between forms of self-expression whose authors became increasingly aware of the distinction between the act of remembering and the act of writing. The book focuses on the literary works of Gregory of Nazianzus (329/330 - 389/390), the Cappadocian theologian and poet who is believed to have produced the first large-scale corpus of autobiographical poetry (nearly 7,000 verses) in Europe. The individual chapters address a range of issues related to self-representation in Late Antiquity: the methods of reflecting reality in art, the theological and philosophical frameworks of self-perception, poetic imagery and topoi. They also discuss Gregory’s oscillation between sincerity and didacticism, in line with the ancient conception of the individual as inseparable from society. The heart of the book, however, is the complete translation of Gregory’s autobiographical poetry as it appears in the 37th volume of Jacques-Paul Migne’s Patrologia Graeca (1857) and in more recent critical editions. The poems, rendered in a syllabotonic imitation of classical metres, are accompanied by indexes and extensive footnotes. The reader can thus enjoy an unconventional portrait of a saint who dared to combine lyrical lamentation with irony and even sarcasm.

2025

In this bachelor's thesis I will focus on Kendall Walton's interpretation of the theory of emotions evoked by fiction, presented primarily in his book Mimesis as Make - Believe: On the Foundations of the Representational Arts and a number of articles. First, I will analyse how in general Kendall Walton views the nature of emotions experienced in perceiving fiction. I will deal with the term "game of make - believe", which Walton introduces to describe the reader's or the viewer's experience with fiction. Using the concept of game of make - believe Walton points out the character of the emotions evoked by fiction. I will perform a comprehensive analysis of Walton's term "quasi - emotions". The bachelor's thesis will be divided into two main parts. In the first part, I will interpret Walton's studies. In the second part, I will approach the topic critically and confront his thesis with the arguments by Noël Carroll and Richard Moran, who...

2025, Revista Orto

Artículo de Carlos Coca, en la revista "Orto" (número 216, sep.-dic. 2024).

2025, In: Acta historica Universitatis Silesianae Opaviensis, vol. 17/2024, pp. 11-27. ISSN 1803-411X. ISBN 978-80-7510-596-7.

Laments of Saint Gregory of Nazianzus — This article examines sixteen autobiographical poems by Gregory of Nazianzus, devoted to the sorrowful complaints of an ageing clergyman. The main aim is to determine whether, on the basis of their formal and thematic characteristics, they can be regarded as examples of a particular genre. The answer seems to be yes, although it is clearly not a genre that fits into the system established in the Archaic and Classical periods of Greek literature. There is no doubt that Gregory uses certain elements of the ancient Greek θρῆνος and ἐλεγεία, but he relies much more heavily on genre patterns derived from Old Testament poetry. It seems more appropriate, then, to speak of a distinct variant of the lament genre, dominated by the motifs of sickness, rebellious and lustful flesh, and death, understood as the gateway to freedom. In general, Gregory’s laments combine life experience with fiction, and didactic intention with private expression of grief. However, their tone is not bleak and hopeless, for they follow the lament-to-praise structure found, for example, in Psalm 22 (21).

2025, Autobiografie. Ricerche, pratiche, esperienze

Il contributo nasce dal gruppo di lavoro sul tema Autobiografia e educazione all'interno del Simposio Dialoghi intorno all'Autobiografia svoltosi ad Anghiari il giorno 7 dicembre 2019. Le pratiche di educazione alla memoria, alla lettura, alla narrazione e alla scrittura autobiografica hanno acquisitoin particolare negli ultimi venti anni -uno spazio rilevante e sempre più necessario nei luoghi dell'educazione formale e non formale. La scuola di formazione della Libera Università dell'Autobiografia di Anghiari, a partire dal 1999, ha promosso corsi ed eventi per l'apprendimento e il miglioramento di conoscenze e competenze sulla pedagogia e didattica dell'autobiografia. Il contributo, scritto da tre docenti di differenti aree pedagogiche (storicoeducativa, didattica e pedagogico-sociale), fa riferimento a teorie e strategie per favorire un processo formativo e auto-formativo: fare storia, leggere, scrivere di sé e raccontare comunità. Una sfida per una nuova umanizzazione, a partire dall'educazione alle storie. This contribution discusses the results from a working group on the topic "Autobiography and education" within the Symposium 'Dialogue in Autobiography' held in Anghiari on December 7, 2019. The educational practises concerning memory, reading, narration and autobiographical writing have found an important and growing place in formal and informal education, especially over the last twenty years. Since 1999, the Free University of Autobiography in Anghiari training school has organized courses and events for students to learn * Gianfranco Bandini è professore ordinario di Storia della Pedagogia, dirige il progetto "Memorie di scuola" e un gruppo di ricerca sulla Public History ed è membro del consiglio scientifico del Centro Nazionale di Ricerche e Studi Autobiografici "Athe Gracci". ** Federico Batini è professore associato di Didattica, dirige la Rivista Lifelong Lifewide Learning e coordina i seguenti progetti di ricerca: Leggere:forte e Leggimi ancora. *** Caterina Benelli è ricercatrice di Pedagogia generale e sociale, dirige la Rivista Autobiografie, è coordinatrice dell'area progetti e ricerche della LUA ed è membro del consiglio scientifico del Centro Nazionale di Ricerche e Studi Autobiografici "Athe Gracci". Autobiografie. Ricerche, pratiche, esperienze and gain a wider knowledge and skills regarding autobiographical pedagogy and teaching methods. This contribution is authored by three professors from different pedagogical areas (historical-educative, teaching and pedagogicalsocial) and discusses theories and formative strategies for promoting learning and self-training processes, i.e., making history, reading, life-writing and community sharing. This poses a challenge for a new humanisation, moving from education to the stories. Quando ci si confronta con la storia, soprattutto nei percorsi scolastici, in genere si affronta uno studio che tende a differenziare con cura tra storia e memoria, a rimarcarne bene gli aspetti di alterità, piuttosto che quelli di affinità. La prima ha una serie di caratteristiche scientifiche e oggettive, la seconda è il terreno privilegiato della soggettività e della molteplicità dei punti di vista. Questo modo dicotomico di affrontare il nostro passato ha sollecitato molti dibattiti e anche accese e lunghe discussioni. Probabilmente, ma forse non del tutto, abbiamo superato questa contrapposizione: lo sviluppo della storia orale, per esempio, ne è la prova più esplicita e convincente. Negli ultimi anni nel panorama degli studi storici si sta affacciando in Europa, e in primo luogo in Italia, un approccio nord americano che ha al suo attivo già alcuni decenni di teorizzazioni e sperimentazioni: la public history. È proprio questo tipo di approccio che risulta quanto mai interessante per ricollegare storia e memoria, accademia e pubblico, ricerca teorica e comunità locale. La tipica demarche della public history prevede infatti un forte coinvolgimento delle persone, delle collettività, e di tutto il loro patrimonio di ricordi, immagini, oggetti. Un universo di significati e di esperienze, cognitive e affettive, che può essere esplorato in molti modi. E in molti modi possono essere creati dei legami, delle contaminazioni e anche delle vere e proprie co-costruzioni dei significati storici. Renderci conto di questi aspetti significa offrire a molte persone, ma in particolare a tutti coloro che vivono all'interno di contesti educativi formali, la possibilità di utilizzare questo grande patrimonio, di contribuire a arricchirlo e comunicarlo. È utile, a questo punto, soffermarci un attimo sul ruolo sempre maggiore che le testimonianze, nelle loro varie tipologie, svolgono nella cultura contemporanea e nella comprensione intellettuale del passato. Se utilizziamo Ngram Viewer 2 possiamo avere una conferma, visivamente molto chiara e interessante, di questa linea di tendenza. Si tratta di un software recentemente sviluppato da Google, utilizzato ad esempio dagli specialisti di linguistica, che consente di esplorare la ricorrenza di alcuni termini all'interno di vasti databases di libri. Se scegliamo

2025, Unbelonging in Postcolonial Literature

Greene’s position at the Foreign Office, as well as his travels around the world’s most chaotic regions during the most chaotic period of human
history, makes him an ideal specimen for analyzing the personal histories and encounters of a colonizer and a colonized figure in such times. At this time, Zadie Smith claims that Greene has witnessed some of the world’s most tumultuous battles and that people are still battling over old grievances (2004, p. viii). One of Greene’s most astute insights is the complication with which a definitive intervention is necessary for the characters’ acts. This challenge throughout Greene’s world stems mainly from humanity’s mutual influences and partly from his ethical principles. The combination of powers inside and out of the human soul generates the feeling of an unseen requirement that seems to regulate the main
character’s decisions at critical points. It is driven by his early childhood
memories, a Christian and perhaps spiritual code, or irrational anxieties and wishes. The powers of systemic racism, cruelty, crime, and corruption, which embody the fading authority of wickedness, are challenging to reverse.

2025, Psychologica

Autoři příspěvku představují model narativně orientovaného výzkumu. Šest přístupů k analýze a interpretaci je demonstrováno na příběhu ženy trpící rakovinou prsu: syžetobsahová, holisticko-obsahová, holisticko-formální, kategoriálně-obsahová, kategoriálněformální, kritická narativní analýza. Narativní analýza a interpretace se překrývají, což vyžaduje důraz na transparentnost jako základního principu kvalitativního výzkumu a aplikaci hermeneutických principů rozumění. narativní analýza, přístupy k interpretaci narativit, transparentnost Tato studie je součástí výzkumného záměru PSÚ AV ČR (AV0Z70250504) a byla podpořena GA ČR (406/06/1577). Když se účastníků výzkumu zeptáme, aby řekli něco o své zkušenosti nebo vysvětlili nějaký aspekt svého života, obvykle použijí narativní modus, tj. nabídnou popis, který má strukturu příběhu. Je zřejmé, že nestrukturované či semi-strukturované interview částečně posilují vynoření tohoto narativního modu. Ale narativní výzkum není jen metodou sběru či analýzy dat, je to pole výzkumu per se. Obecná východiska narativního přístupu jsme pojednali jinde , 2006. Tématem tohoto příspěvku je výzkumný postup, který postupně vykrystalizoval v průběhu posledních patnácti let a který jsme s Davidem Hilesem a Vladimírem Chrzem nazvali Narativně orientovaný výzkum (Narrative Oriented Inquiry -NOI). Model NOI vychází z psychologicky zaměřených přístupů k narativnímu výzkumu a zásadním způsobem zahrnuje jak proces sběru dat, tak také širokou škálu přístupů k analýze a interpretaci těchto dat. V rámci tohoto modelu zdůrazňujeme výzkum osobních narativit,

2025, Zeitschrift für Germanistik, N.F. 35:1, 226–229

2024

### Abstract The decolonization era from the 1950s brought significant changes in theological discourse and biblical translations, emphasizing localized and inclusive interpretations of Christianity. This article explores the emergence... more

2024, Новое литературное обозрение

Статья посвящена беллетристике Авдотьи Панаевой. Ее сочинения рассматриваются как источник для реконструкции субъектности писательницы. Проанализированная под таким углом зрения, ее проза позволяет объяснить, как Панаева, единственная сотрудница «Современника», относилась к прогрессивным декларациям и повседневным практикам мужской редакции журнала. В статье также подробно обсуждаются как особенности прозы Панаевой (прототипизм, эмансипационная программа), так и литературная репутация беллетристки, в частности пересматривается ее уход из литературы на несколько десятилетий после публикации романа «Женская доля» (1862). Хотя прогрессивный проект Панаевой в силу исторических обстоятельств оказался невостребованным современниками, ее прозаическое наследие дает исследователям возможность посмотреть на редакцию «Современника»
женскими глазами.

2024, Le ferite del guaritore

Questo lavoro nasce dalla mia personale urgenza di dare senso e significato all'esperienza della malattia, un'esperienza che ho vissuto in prima persona come paziente oncologico. Durante il mio percorso di cura, ho avuto modo di confrontarmi direttamente con ogni aspetto dell'attuale condizione del sistema sanitario in Italia e del concetto stesso di cura, con tutte le sue difficoltà, criticità e complessità. Pur riconoscendo come l'ambiente sanitario italiano sia considerato tra i migliori al mondo, ho percepito fortemente la necessità di un cambiamento di paradigma. Si parla spesso di "umanizzazione delle cure" come se i professionisti della salute avessero in qualche modo perso la propria umanità. Tuttavia, questa disumanizzazione non è imputabile ai medici, agli infermieri o agli altri operatori sanitari, ma piuttosto a un sistema economico-produttivo che ostacola la possibilità di creare un setting e un rapporto tra curante e paziente che sia realmente rispondente ai bisogni reciproci.
Nel corso del tempo, le unità sanitarie locali hanno subito una trasformazione significativa: da enti dediti alla cura e al benessere delle persone, sono state gradualmente convertite in "aziende sanitarie", con una conseguente perdita di focus sul loro obiettivo primario. La cura è stata delegata quasi esclusivamente agli aspetti numerici e produttivi della medicina basata sull'evidenza (Evidence Based Medicine), una pratica che, pur necessaria, ha finito per distogliere l'attenzione dal vero significato della cura. Questo approccio tende a considerare come successi unicamente la guarigione o il miglioramento dei sintomi, trascurando completamente la qualità della vita, sia dei pazienti che dei curanti.
Nel mio percorso, ho sentito il bisogno di andare oltre questa visione riduttiva e ho deciso di creare un laboratorio di Scrittura Creativa per pazienti oncologici, presentato anche presso la facoltà di Medicina e Chirurgia dell'Università di Tor Vergata di Roma. Il progetto, intitolato Aiutami a raccontare, ha ottenuto grande consenso e interesse, ponendo l'accento sulla relazione di aiuto che ogni forma terapeutica dovrebbe necessariamente includere. La scrittura diventa così uno strumento per dare voce al vissuto del paziente, permettendogli di esprimere il proprio dolore, le proprie paure e i propri desideri, in un contesto che valorizza la narrazione come parte integrante del processo di cura.
Il titolo del presente lavoro trae ispirazione dall'archetipo junghiano del guaritore ferito1. Nella mitologia greca, Chirone, il guaritore ferito per eccellenza, non solo cura gli altri attraverso l'esperienza del proprio dolore, ma trova nella cura degli altri una forma di guarigione per sé stesso. Questo archetipo rappresenta l'urgenza di dare risposta al proprio soffrire e di trovare un senso e una direzione attraverso l'azione. È un'immagine potente che risuona profondamente con l'esperienza di molti pazienti oncologici, che trasformano il loro dolore in un motore per aiutare gli altri e per rinnovare il proprio impegno verso la vita.
Riflettendo su questo tema, mi sono accorto che la risposta del paziente oncologico, in termini di adattamento creativo, spesso si traduce in un'azione diretta sulla società, un'azione che può essere definita politica nel senso più alto e nobile del termine. Questo lavoro, che si configura quasi come una ricerca sul campo in termini narrativo-antropologici, raccoglie una serie di testimonianze che ho raccolto durante le interviste con persone che ho incontrato nel mio percorso di guarigione. Utilizzo il termine "guarigione" non nel suo senso bio-clinico, ma come un processo che porta a ristabilire significato e valore all'esperienza della malattia.
In questo contesto, l'arte, lo sport e l'impegno sociale diventano risposte attive che permettono di trascendere i termini quantitativi della malattia, per focalizzarsi su una qualità della vita che riflette la definizione olistica di salute fornita dall'Organizzazione Mondiale della Sanità: "La salute è uno stato di completo benessere fisico, emotivo, sociale e spirituale, non solo assenza di malattia". Questa visione olistica della salute è fondamentale per comprendere il ruolo della cura e dell'autoespressione nel processo di guarigione, e per riconoscere che la qualità della vita non può essere ridotta a semplici numeri o parametri clinici.

2024

Recenze na knihu Maksym Dupeško: Za všechna jablka světa… Z ukrajinského originálu Історія, варта цілого яблуневого саду (2017) přel. Jekaterina Gazukina, Tereza Chlaňová, Alexandra Vojtíšková. Červený Kostelec: Pavel Mervart 2024, 166... more

2024, HAL (Le Centre pour la Communication Scientifique Directe)

È¤aeÚU ßÇü U Âý ð â Õé €â ¥aeßÚU ‡ae Ñ Ò¥aeñ çCþ U •¤ ß Âàaeé ÂaeÜ•¤ ×çãU áaeâé ÚU Ó, ÜaeÜ ÚÛÙae•¤ÚU çÇU Áae §U Ù-Üð ¥ae©U ÅU Ñ ÚU aeÁÙ •é ¤×aeÚU ×é Îý •¤ Ñ çß•¤aeâ •¤OEØê ÅU ÚU °ḈU çÂý ÅU âü , ÙßèÙ àaeaeãÎÚU aeU , çÎ"è-110032 ×çãU áaeâé ÚU Ñ °•¤ ÁÙÙaeØ•¤ (âŚ•ë ¤çÌ çß×àaeü) âẤaeÎ•¤ Ñ Âý ×aeð Î ÚÚ ÁÙ MAHISHASURA : EK JANNAYAK (A Discourse on Culture) Edited by Pramod Ranjan 5 ÁÙç¿ÌÙ •Ô ¤ âÚU ô•¤aeÚU ¥Ùé •ý ¤× Öê ç×•¤ae (h)°• ¤ âaeŚ•¤ë çÌ•¤ Øé h (uhh) ¹ ‡Ç Ñ 1-Âé ÙÂaeü AE ç•¤â•¤è Âê Áae •¤ÚU ÚU ãð U ãñ U Õãé U ÁÙ? Âý ð ×•é ¤×aeÚU ×ç ‡ae ãˆØae¥ô´ •¤ae ÁàÙ €U Øô? Âý ð ×•é ¤×aeÚU ×ç ‡ae ÎàaeãÚU ð •ð ¤ ˆØôãaeÚU ÂÚU Âý ð ×•é ¤×aeÚU ×ç ‡ae ¥âé ÚU ãôÙð ÂÚU ×é Ûaeð »ßü ãñ çàaeÕê âôÚU ð Ù âÍaeÜ âãaeÚU •¤ Îé »aeü ×Ïé Ÿaeè ×é ¹Áèü ×ŠØ Âý Îð àae-Àžaeèâ»É¸ ×ð ¥âé ÚU ÂÚÚ ÂÚU ae°´ÚU aeÁÙ •é ¤×aeÚU ÎçÜÌ-Õãé ÁÙ Îë çC•¤ô ‡ae ¥õÚU ×çãáaeâé ÚU çß×àaeü Õý Á ÚÚ ÁÙ ×ç ‡ae Öaeáaeçß™aeaeÙ •¤è Îë çC ×ð ×çãáaeâé ÚU ÚU aeÁð ‹Îý Âý âaeÎ çâã Îé »aeü •¤ae ×õçÜ•¤ SßM¤Â Ùê ÌÙ ×aeÜßè ×çãáaeâé ÚU ¥õÚU ÕÜè Âý çÌÂÎae »ð Ü ¥aeò ßð ÅU ×çãáaeâé ÚU , ÚU aeß ‡ae ¥õÚU ×ãaeÕÜè ¥ÁØ °â. àaeð ¹ÚU ¹ ‡Ç-2-âaeŚ•¤ë çÌ•¤ Øé h°• ¤ âaeŚ•¤ë çÌ•¤ ¥aeÎôÜÙ •Ô ¤ ¿aeÚU âaeÜ Âý ×ôÎ ÚÚ ÁÙ ß ÚU çß Âý •¤aeàae Õãé ÁÙ çß×àaeü •Ô ¤ •¤aeÚU ‡ae çÙàaeaeÙð ÂÚU ¥aeØae Áð°ÙØê Âý ×ôÎ ÚÚ ÁÙ Ùãè´ L¤•Ô ¤»ae âaeŚ•¤ë çÌ•¤ âƒaeáü •¤ae¿ae ¥aeØÜñ Øae ×çãáae •Ô ¤ Âÿae ×ð •¤óaeÇ¸ Õé çhÁèßè°×. çÎÜèÂ •é ¤×aeÚU Àžaeèâ»É¸ ×ð ×çãáaeâé ÚU •ð ¤ ßàaeÁô´ •¤ae çßÎý aeð ãU ÙḉÎÙè âé ÎÚU ×çãáaeâé ÚU •¤è Õð ÅU è •¤ô ÚU aeCþ ÂçÌ Ùð çÎØae â×aeÙ âÁèß ¿‹ÎÙ ×ãaeÂý ÌaeÂè ×çãáaeâé ÚU •¤è ßàaeÁ âé á×ae ¥çEÙè •é ¤×aeÚU Â•¤ÁU Îé »aeü , ×çãáaeâé ÚU ß ÁaeçÌ •¤è ÚU aeÁÙèçÌ ÚU ae× Âé çÙØaeÙè ×ñ Îé »aeü Âê Áae €U Øô´ Ùãè´ ×ÙaeÌae Šaeý é Õô 'ØôçÌ ×çãU áaeâé ÚU çÎßâ âð âṌḉŠaeÌ Ì‰Ø Üð ¹•¤ ÂçÚU ¿Ø 000 ÚU ae×aeâae×è Âð çÚU ØaeÚU •ð ¤ Âý çÌçÙçŠae çß¿aeÚU ÚU ae×aeâae×è Âð çÚU ØaeÚU •ð ¤ Âý çÌçÙçŠae çß¿aeÚ (i) çÖ€¹é Õaeð ŠaeaeÙÎ ¥aeñ ÚU Õãé U ÁÙ âaeŚ•ë ¤çÌ•¤ ¥aeÎaeð ÜÙ ×ñ ¥ÂÙè ÕaeÌ ×ãaeÙ Õãé ÁÙ ç¿Ì•¤ çÖ€U ¹é ÕôÏaeÙÎ •Ô ¤ °•¤ ©hÚU ‡ae •Ô ¤ ×aeŠØ× âð •¤ãÙae ¿aeãế »ae, Üð ç•¤Ù ©â•Ô ¤ ÂãÜð ×é Ûaeð ¥aeÂ•¤aeð çÖ€U ¹é ÕôÏaeÙÎ •Ô ¤ ÕaeÚU ð ×ð ÕÌaeÙae ÂÇð »aeÐ Øã ç•¤ÌÙè ¥ÁèÕ ÕaeÌ ãñ ç•¤ ¥aeÁ ÁÙâae×ae‹Ø ¥õÚU ã×aeÚU ae Õõçh•¤ â×aeÁ Öè ©Ù•Ô ¤ Ùae× ¥õÚU ßḉ¿Ì â×é ÎaeØô´ •Ô ¤ çÜ° ©Ù•Ô ¤ maeÚU ae ç•¤° »° Õãé ¥aeØae×è •¤aeØaeð Z âð ¥ÂçÚU ç¿Ì ãñ Ð âÙ÷ v}|y ×ð °•¤ Õý aerae ‡ae ÂçÚU ßaeÚU ×ð Âñ Îae ãé° ÕôÏaeÙÎ Õ¿ÂÙ ×ð ãè ¥ÙaeÍ ãô »° Íð Ð ©‹ãð •¤aeàaeè ×ð ÚU ã ÚU ãè ©Ù•¤è çßÏßae ×õâè Ùð ÂaeÜaeÐ •¤aeàaeè ×ð °•¤ çßÏßae •Ô ¤ ¥ae¿Ü ÌÜð ÂÜ ÚU ãð ÕôÏaeÙÎ Ùð Õý aerae ‡aeßaeÎ •¤ae •ñ ¤âae ¥àÜèÜ ¿ð ãÚU ae Îð ¹ae ãô»ae, ã× §â•¤è •¤ËÂÙae ÖÚU •¤ÚU â•¤Ìð ãñ Ð Øé ßae ãôÙð ÂÚU ßð Õý aerae ‡aeßaeÎ •Ô ¤ •¤^U U ÚU çßÚU ôÏè ÕÙð ÌÍae çÂÀÇô´ ¥õÚU ÎçÜÌô´ •¤ô §ââð ×é çQ¤ çÎÜaeÙae ©Ù•¤ae ×•¤âÎ ÕÙ »ØaeÐ x® ßáü •¤è ©×ý ×ð v~®y ×ð ©‹ãôÙð Õõh Ï×ü Sßè•¤aeÚU •¤ÚU çÜØaeÐ ©Ù•Ô ¤ ãè Âý Öaeß ×ð Ç aeò. Öè×ÚU aeß ¥aeṌð Ç•¤ÚU ¥õÚU ÚU aeãé Ü âae•¤ëØaeØÙ âÚU è¹ð Üô» Öè Õõh Ï×ü •¤è ¥ôÚU Âý ð çÚU Ì ãé°Ð ÇU aeò. ¥aeṌð Ç•¤ÚU Ìô ©Ù•Ô ¤ Âý Öaeß ×ð ƒaeǺU ô´ Õñ AEÙae ÂâÎ •¤ÚU Ìð Íð Ð 1 çÖ€U ¹é ÕôÏaeÙÎ •Ô ¤ çß¿aeÚU ô´ Ùð v~x® •Ô ¤ Îàae•¤ ×ð Ù çâÈü Õõh ¥aeÎôÜÙ •¤ô°• ¤ ÙØae ×ôÇ¸ çÎØae, ÕçË•¤ ¥ÂÙð â×Ø ×ð ©žaeÚU ÖaeÚU Ì •¤è çÂÀÇȩ ¥õÚU ÎçÜÌ ÁaeçÌØô• Ô ¤ Õè¿ °•¤ ÃØaeÂ•¤ âaeŚ•ë ¤çÌ•¤-ßñ ¿aeçÚU •¤ ¥aeÎôÜÙ ¹Çae •¤ÚU çÎØaeÐ Ü¹Ùª¤ •Ô ¤ çÚU âaeÜÎaeÚU Âae•¤ü çSÍÌ ©Ù•¤ae Õé h çßãaeÚU ©â â×Ø •Ô ¤ Âý ×é ¹ Õãé ÁÙ Õé çhÁèçßØô• ¤ae •ð ¤Îý ¥õÚU ©Ù•Ô ¤ çß¿aeÚU ô´ •¤ae Âý âaeÚU ‡ae SÍÜ ÕÙ »Øae ÍaeÐ çÖ€U ¹é ÕôÏaeÙÎ Ùð °•¤ ç•¤ÌaeÕ çÜ¹è Íè-Ò×ê Ü ÖaeÚU Ìßaeâè ¥õÚU ¥aeØü ÓÐ §â•¤ae âẤaeÎÙ ¥õÚU Âý •¤aeàaeÙ v~x® ×ð ¿ḉÎý •¤ae Âý âaeÎ çÁ™aeaeâé Ùð çÙáaeÎ ÁaeçÌ •Ô ¤ çßÏaeÙ Âaeáü Î (©žaeÚU Âý Îð àae) ÚU aeØâaeãÕ ÕaeÕê ÚU ae×¿ÚU ‡ae Áè •Ô ¤ ¥aeçÍü •¤ âãØô» âð ç•¤Øae ÍaeÐ ßãU ç•¤ÌaeÕ ©â â×Ø ¿Üð ¥aeÎôÜÙ •¤ae ¥aeÏaeÚU ÍèÐ ©â ç•¤ÌaeÕ ×ð €U Øae Íae, ©â•¤ae ¥Ùé ×aeÙ ¥ae»ð çÖ€U ¹é ÕôÏaeÙÎ maeÚU ae •¤è » §ü U °•¤ çÅU OEÂ ‡aeè âð ãô Áae°»aeÐ Üð ç•¤Ù ©ââð ÂãÜð Îð ¹ð ç•¤ ¿ḉÎý •¤ae Âý âaeÎ çÁ™aeaeâé •¤ô §â »ý Í •Ô ¤ Âý •¤aeàaeÙ •Ô ¤ â×Ø €U Øae ¥aeàae•¤ae°´ ÍèÐ çÁ™aeaeâé Áè Ùð ©U â ç•¤ÌaeÕ •Ô ¤ Ò»ý Í ÂçÚU ¿ØÓ ×ð çÜ¹ae Íae Ñ ÒÒÜô» •¤ãÌð ãñ ç•¤ °ð âae »ý Í Îð àae ×ð Èê ÅU Âñ Îae •¤ÚU ð »aeÐ ßð ØçÎ Øã ÁaeÙÌð ãé° °ð âae •¤ãÌð ãñ ç•¤ (§U â »ý Í ×ð •¤ãU è » §ü U) ÕaeÌ Ìô â¿ ãñ , ÂÚU §â â×Ø §â•Ô ¤ •¤ãÙð •¤ae Öê ç×•¤ae (ii)

2024

La LIJ como literatura de resistencia. Impugnación al olvido Tamara Sotelo "Si esto es un hombre: los que vivís seguros en vuestras casas caldeadas los que os encontráis, al volver por la tarde, la comida caliente y los rostros amigos: Considerad si es un hombre quien trabaja en el fango, quien no conoce la paz, quien lucha por la mitad de un panecillo, quien muere por un sí o por un no. Considerad si es una mujer quien no tiene cabellos, ni nombre, ni fuerzas para recordarlo, vacía la mirada y frío el regazo como una rana invernal. Pensad que esto ha sucedido: Os encomiendo estas palabras. Grabadlas en vuestros corazones al estar en casa, al ir por la calle, al acostaros, al levantaros; repetídselas a vuestros hijos. O que vuestra casa se derrumbe, la enfermedad os imposibilite, vuestros descendientes os vuelvan el rostro." Primo Levi. Si esto es un hombre 1 Hablar de Literatura y Memoria, automáticamente nos remite a un tema vinculado con el momento histórico más nefasto de nuestro país: la última dictadura militar argentina. Igualmente, no sólo nuestro país fue víctima del terrorismo de Estado, sino que países hermanos de Latinoamérica y Europa sufren, hasta hoy, las consecuencias de estos sistemas oscuros (nunca azarosos), marcando en la subjetividad de los pueblos, que aún sangrando, intentan recuperar los espacios de libertad perdidos y arrebatados por la naturalización de los diferentes procesos sociales. La literatura, en su praxis específica, ha sostenido a lo largo del tiempo, la posibilidad de eludir al olvido social. Posiblemente no sea éste el objeto en sí de la literatura, si es que lo tiene, pero cuando hablamos de Primo Levi en Si esto es un hombre, de Benedetti en La otra orilla, de Piglia en Respiración artificial, de Heker en El fin de la Historia, de Kohan en Dos veces Junio, de Kafka en El proceso y de tantos otros autores que han literaturizado la historia, creando la posibilidad de resignificar las lecturas de la misma, decimos que, desde nuestro punto de vista, si no es la función literaria modificar a partir de la reflexión, su función entonces es desconocida y gozará, seguramente, de buena salud. Juan José Saer, diría al respecto: "La función de la literatura no es la de corregir la distorsiones a menudo brutales de la historia inmediata, ni producir sistemas compensatorios, sino, por el contrario, es la de asumir la experiencia del mundo en toda su complejidad, en sus indeterminaciones, y en sus oscuridades, y tratar de forjar, a partir de estas complejidades, formas, que la distingan y la representen." (Saer 1989

2024, Temida 2, Przy współpracy i wsparciu finansowym Wydziału Filologicznego Uniwersytetu w Białymstoku eBooks

Szczypta biografii Józefa Śmigielska urodziła się 15 października 1820 roku w Warszawie jako najstarsza z sześciorga dzieci Walentego Śmigielskiego i Karoliny Bonieckiej. Niewiele wiemy na temat jej rodziny, miała zapewne czterech braci i jedną siostrę. Pewne jest natomiast, że bardzo wcześnie doceniła rolę wykształcenia w życiu kobiet. Był to zapewne efekt z jednej strony edukacji pobieranej w Instytucie Wychowania Panien 1 , gdzie uczyła się od 1833 roku, z drugiej zaś, zasługa sprzyjającego jej zamierzeniom edukacyjnym owdowiałego ojca. Często pisała o doświadczeniach młodości, widząc w nich przyczynę swego późniejszego zaangażowania w sprawy kobiet: Nie brakło mi na utrzymanie w domu ojca mego, ale mnie wyparła z niego żądza wyrobienia sobie samej chleba i pozycji w świecie. To pragnienie było we mnie nieodłączne od uczucia godności człowieka i jakakolwiek bierność, na którą skazane są kobiety, stawała mi nieraz w poprzek drogi, jednak nigdy nie ostudziła energii moich usiłowań. […] Kochałam naukę, to już zaś jest wielkim grzechem dla kobiety i z wielką wyrozumiałością wszystkie inne jej darują, ależ ambicja wyrobienia sobie chleba i pozycji w społeczeństwie, która w mężczyźnie szlachetnością się nazywa, 1 Instytut, o którym tu mowa, powstał z połączenia pensji Zuzanny Wilczyńskiej i Szkoły Guwernantek. Podstawowe informacje na temat życia pisarki znaleźć można m.in. w notach:

2024, Apresentação na 9ª Jornada de Pós-Graduação da UNIRIO

Este trabalho tem por objetivo apresentar uma discussão bibliográfica pertinente à pesquisa de doutorado desenvolvida no Programa de Pós-Graduação em História da Unirio pelo bolsista. Tal discussão se configura como debate extenso, ao qual não se pretendeu a totalização, mas o levantamente de caminhos de reflexão relevantes para o estudo da obra de um acadêmico do século XIX. Para tanto, se desenvolveu o debate entre percepções distintas sobre as questões atinentes à biografia e à autobiografia enquanto fontes históricas, o que possibilitou esclarecer caminhos interpretativos e pontos espinhosos que requerem um cuidado maior quando do trato com as fontes onde se busca recolher informação minimamente objetiva para a historicização do autor estudado no período específico em que nos propomos a estudar, período este que é pouco estudado pela bibliografia especializada.

2024, Svět literatury

Recenze na: Kudlová, Klára. Čas, postavy, román: Na přelomu tisíciletí. Brno — Praha: Host — Ústav pro českou literaturu, 2023, 216 s. Vyšlo v Svět literatury 70, 2024, č. 2, s. 177-181.

2024, Thesis

This thesis focuses on the process of phenomenologically dwelling in selected works of children’s fiction. It was undertaken against a backdrop of disconnect from the teaching profession and a need to reconnect with private and professional self. The thesis opens by acknowledging the conditions that sometimes pull teachers out of their zone of flow, or their in-teacher-ness. It recognises that revisiting lived experiences, and understanding their essence, may shed light on the nature of these conditions. A theoretical framework is established, upholding the value of perception in phenomenology, the way intentionality affects our interactions with the world, and the meaning of being. A secondary framework of autobiographical writing is also applied, encouraging authentic writing of self. The value of fiction as truth-seeking material is debated, concluding that its readers can employ imagination, study emotions and gain self-understanding. The thesis is then structured like a journey, set out in methodological steps underpinned with theoretical literature and evidenced by autobiographical writing outcomes about remembered lived experiences. Using childhood fiction, and stories used professionally in the classroom, each incremental step involved in text-dwelling is documented and theoretically scrutinised. The final stage explores writing authentically with intentionality. It is suggested that dwelling in fiction, and understanding the impact of in-conscientious-ness on work ethic and mindset, can explain some of the conditions affecting in-teacher-ness. There is an emphasis on employing these dwelling steps for teachers and pupils, concluding that the process sits comfortably alongside current reflection tools taught in initial teacher training and professional settings.

2024, Moysidou, Stella–Alkistis. 2024. “Pre-Raphaelite Intertextualities, Romantic Aesthetics and Love As Melancholy in Constantin Christomanos’ Tagebuchblätter (1898)”. Brolly 5 (2):31-45. https://journals.lapub.co.uk/index.php/brolly/article/view/2784

AI-Driven Building Architecture. Ethics, Sustainability and Optimization 235 Elizabeth Tofunmi Ojelabi and Emmanuel Olusegun Adekunle completed only through decay and death 'among the ruins'.

2024, Les Cahiers de l'ILCEA

Mémoire et indicible : la question du trauma individuel dans les arts contemporains (récit, poésie et cinéma) Une retenue infinie : le deuil et la douleur dans l'oeuvre autobiographique de Natalia Ginzburg

2024, Perspectives in Education

Since the outbreak of the coronavirus pandemic, socioeconomic inequalities have become exacerbated and COVID-19 related hate crimes have increased. This paper explores how citizenship education might be reimagined in response to this context, with the vision of rebuilding a more equitable and compassionate society. By using a collective autobiographical writing approach, this study documented six different autobiographical reflexivities of citizenship education scholars who were from different parts of the world: China, South Korea, the Philippines, the United States, Nepal and the United Kingdom. It also observed the way the pandemic played out in the location where they were situated during the research as well as how it played out in their countries of origin, and further, how it affected the civic development in each context. The scholars' range of autobiographical expressions resulted in insights for developing a type of citizenship education, namely, education for active and compassionate citizenship.

2024

Bodily disintegration and successful ageing in Body Bereft by Antjie Krog Antjie Krog's Body Bereft (2006) details both the bodily changes brought about by older age and the ways in which these changes fracture a person's previously-stable sense of self. This article reads Krog's depiction of the ageing body in a small selection of poems from this collection in relation to the unavoidable reality of bodily decay and what is referred to in gerontological theory as 'successful ageing'. This tension dominates large parts of the gerontological field, and can be seen in Krog's ambivalent representation of older age in Body Bereft. Through close readings of a number of poems, I will investigate the ways in which Krog problematises the relationship between the lived experience of older age with its concomitant sense of deterioration, and the societal impetus to age well and accept ageing with magnanimity. I will demonstrate that this collection foregrounds the poet's refusal to accept pre-existing discourses that delimit ageing as something either to bemoan or celebrate. I will conclude that this refusal finds particular expression in her poems "dommelfei / crone in the woods" and "how do you say this".

2024, Rúbrica Contemporánea

Las figuras de dos destacados anarquistas granadinos, Francisco Galadí y Juan Arcoya, son bien conocidas por los relatos franquistas, primero, y lorquianos después, correspondiendo a la atención de un público más interesado en los aspectos culturales de una España romantizada en el extranjero frente a los movimientos sociales y políticos existentes. En el presente trabajo se abordarán las facetas laborales y militantes de estos dos ácratas granadinos y se rescatará una tercera figura también relacionada con el anarquismo y el mundo del toreo: la de Antonio Paniza. Se analizará la relación de la tauromaquia con el anarquismo por medio de artículos y los casos de estos anarquistas.

2024, Cahiers de Civilisation espagnole contemporaine

CÉSPEDES GALLEGO Jaime, «El discurso anarquista en dos documentales sobre la II República y la Guerra Civil realizados durante la Transición» ("Entre la esperanza y el fraude: España, 1931-1939" de Cooperativa de Cinema Alternatiu y "Por qué perdimos la guerra" de Diego Abad de Santillán), en Cahiers de Civilisation espagnole contemporaine, nº 14, 2015.

2024, Logos Universality Mentality Education Novelty: Philosophy and Humanistic Sciences

) is a writer that has been completely ignored by literary histories. Her profile is presented only in recent dictionaries and the bibliographical references regarding her activity are limited only to a few dozen titles. In the writer's biography there are still unexplored aspects and sometimes even flaws. Nevertheless, her life was dedicated to cultural values and her literary activity was rewarded with the Alina Ştirbey Prize and with the Academy's Award, which she received three times. The novel "Blandina", written in French and having the subtitle "Une âme s'ouvre à la vie" ("A Soul Opens to Life"), came out in 1980, thirty years after the writer's death, translated by Emilia Şt. Milicescu. An autobiographical novel, a Bildungsroman that restores the life line, the experiences connected to her intellectual and spiritual formation and her burning passion for work, "Blandina" remained, just like the author's other novels, unknown to the public, as well as to the chroniclers of those times. The protagonist crosses a path of self-knowledge, doubled by the achievement of virtues. The path to wisdom is sprinkled, just like in fairytales or in initiatory stories, with tasks that she must accomplish by fighting instincts or vices. Thus, writing becomes a place of searching for one's identity and the ethical dimension is one of the main keys of reading.

2024

All writing worth reading comes, like suicide from outrage or revenge', writes William Gaddis in his novella, Agape Agape (Gaddis 2002, p. 63). These are the words of Gaddis's fictional character, an elderly man with a terminal illness, rambling on about his dissatisfactions at the decline of civilization and grumbling about the book he never managed to write. I take these words, although controversial, as a starting point to my argument that traumatic experience can give rise to feelings of shame, rage and the desire for revenge. If such emotions are harnessed they can lead to creativity, particularly in the autobiographical act of life writing. In arguing for a psychoanalytic object relations approach to trauma, psychoanalyst Caroline Garland, writes that 'trauma touches and disrupts the core of … identity … Trauma is like a wound', she writes (1998, p. 9-11). It pierces the psychic

2024, Jahrbuch der Karl-May-Gesellschaft 2017

Als literarischer Text wurde "Frau Pollmer, eine psychologische Studie" bisher kaum wahrgenommen. Und wenn doch, geschah es häufig mit dem Ziel, diese ungewöhnliche Schrift als Fiktion und ihren Autor als Phantasten zu überführen. Der Beitrag nähert sich der "Studie" hingegen als literarischem und autobiografischem Text. Ausgehend von Hayden Whites Emplotment-Theorie, die Fiktionalisierung als integralen Bestandteil historiografischen Erzählens betrachtet, wird das dem Text zugrundeliegende Narrativ herausgearbeitet und aufgezeigt, dass die Stilisierung Emma Pollmers zur Männer vernichtenden Femme fatale wahrscheinlich eine therapeutische Funktion hatte.

2024

Background: Abiraterone acetate (AA) is approved by FDA as second line treatment for patients (pts) with CRPC that experience disease progression after first line docetaxel chemotherapy. AA is a potent inhibitor of both 17ahydroxylase and 17,20-lyase (CYP17) activity. This inhibition may produce an increase in the concentrations of steroids synthesized upstream of the CPY17, with consequent adverse effects as hypokalemia, fluid retention and hypertension. Patients and Methods: Since November 2011, 28 pts with CRPC treated at IRCCS of Candiolo received AA plus prednisone (5 mg twice daily). Pts had undergone previous treatment with one or more lines of chemotherapy, in particular 89.3% of pts (25/28) had been treated with docetaxel (schedule 75 mg/m 2 1/21), 35,7% of pts (10/28) received two lines of chemotherapy (docetaxel followed by mitoxantrone), 10.7% of pts (3/28) underwent chemotherapy with docetaxel with weekly schedule, one patient was treated with two lines of docetaxel, and one patient with a rechallenge of docetaxel after previous docetaxel and mitoxantrone chemotherapies. Twelve patients are still undergoing treatment with AA. We recorded all grades toxicity (according to NCI-CTACE v 4.0), with special regard to those related to the mineralcorticoid excess that may be induced by AA. Results: All pts included in the study had a good performance status (ECOG 0-1). Median age was 72.5 years (range 54-79) and 10 pts (35.7%) were older than 75 years. Hypertension was the most frequent adverse event and occurred in the totality of pts, though it was not worsened by therapy with AA and only 7 cases (25%) presented grade 3 toxicity. Hypokalemia occurred in 7.1% of pts (2/28), all cases were grade 1, without any indication for prompt correction. The incidence of fluid retention was 14.3% (4/28) and grade 1 or 2 peripheral oedema accounted for most of these events. There was no onset of cardiac arrhythmias. Other common toxicities included back pain (32.1%), fatigue (39.3%), arthralgia (21.4%) diarrhea (18%), vomiting (7.1%) and nausea (7.1%). Anemia occurred in 21% of patients and was of grade 3 in one case. Conclusion: Abiraterone acetate has a very favorable toxicity profile, with low incidence of grade 3 toxicities and is a feasible treatment even for patients with hypertension.

2024, Kapitál 8, 2024, č. 5, s. 22-23

Esej o členovi Skupiny 42.

2024, Journal of Neuro-oncology

Purpose The aims of our retrospective study investigated the role of immune system in glioblastoma (GBM), which is the most aggressive primary brain tumor in adults characterized by a poor prognosis. The recurrence rate remains high, probably due to "immune-desert" tumor microenvironment (TME) making GBM hidden from the anti-tumoral immune clearance. Considering this, we aimed to create a panel of prognostic markers from blood and tumor tissue correlating with overall survival (OS) and progression-free survival (PFS). Methods Firstly, we analyzed the inflammatory markers NLR and PLR as the ratio of the absolute neutrophil count and absolute platelet count by the absolute lymphocyte count respectively, collected at different time points in the peripheral blood of 95 patients. Furthermore, in 31 patients of the same cohort, we analyzed the formalin-fixed paraffin embedded samples to further compare the impact of circulating and inflammatory markers within the TME. Results Patients aged < 60 years and with methylated MGMT showed better OS. While, pre-chemotherapy Systemic Inflammatory Index (SII) < 480 was related to a better OS and PFS, we observed that only CD68+macrophage and CD66b+neutrophils expressed in vascular/perivascular area (V) showed a statistically significant prognostic role in median OS and PFS. Conclusions Thus, we underscored a role of SII as predictive value of response to STUPP protocol. Regarding the TMErelated markers, we suggested to take into consideration for future studies with new immunotherapy combinations, each component relating to expression of immune infiltrating subsets.

2024, Annals of Oncology

Background: Early palliative care (EPC) seems to ameliorate Quality of Life (QoL) of advanced cancer patients but the optimal timing for activating EPC has to be defined. Methods: Four ESMO Designated Centres of Integrated Oncology & Palliative Care (ESMO-DC) randomized pts to receive Standard Oncologic Care (SOC) alone (control arm-C) or integrated with EPC (sperimental armS). Eligible pts had diagnosis, within the previous eight weeks, of advanced NSCLC, gastric, pancreatic and biliary cancers; first line chemotherapy; ECOG PS 0-2. QoL was assessed at baseline (T0) and at 12 weeks (T1) with the FACT-G scale. Primary endpoint was the change in the QoL scores from T0 and T1.

2024, Journal of Clinical Oncology

e15571 Background: Currently, no validated biomarkers are available for second-line anti-angiogenic treatment in RAS wild type (wt) metastatic colorectal cancer (mCRC) patients (pts) progressing after first-line anti-EGFR. Here, we present the results of a pre-planned interim analysis of the DISTINCTIVE trial (NCT04252456) on prognostic groups identified with the combination of hematologic parameters and based on the association of clinical and translational biomarkers. Methods: RAS wt mCRC pts progressing after first line oxaliplatin-based + anti-EGFR therapy receive FOLFIRI-aflibercept and are prospectively stratified in 2 groups according to Elisa-assessed baseline VEGFR2 plasma levels. Other circulating angiogenic factors are evaluated at specific timepoints. Clinical and laboratory data are collected to assess their correlation with outcome. Primary endpoint is overall survival (OS) according to VEGFR2 levels. Secondary endpoints are OS, progression free survival (PFS), respons...

2024, Digestive and Liver Disease

Background: The SARS-CoV-2 pandemic has had a huge impact on healthcare systems, resulting in many routine diagnostic procedures either being halted or postponed. Aims: To evaluate whether the diagnoses of colorectal, gastric and pancreatic cancers have been impacted by the SARS-CoV-2 pandemic in Italy. Methods: A survey designed to collect the number of histologically-proven diagnoses of the three cancers in gastroenterology services across Italy from January 1 to October 31 in 2017-2020. Non-parametric ANOVA for repeated measurements was applied to compare distributions by years and macro-areas. Results: Compared to 2019, in 2020 gastric cancer diagnoses decreased by 15.9%, CRC by 11.9% and pancreatic by 9.9%. CRC distributions showed significant differences between all years, stomach cancer be

2024, Exils et migrations ibériques aux XXe et XXIe siècles

Après être passé par plusieurs camps du Midi, le militant anarcho-syndicaliste espagnol Manuel Sirvent Romero est livré aux Allemands en 1941 et transféré d’Argelès-sur-Mer à Brest dans le cadre de l’Organisation Todt. Il se souvient des... more