BindingDB PrimarySearch_ki (original) (raw)
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human PKAC-alphaMore data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=cAMP-dependent protein kinase catalytic subunit alpha&ids=hsa:5566)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=cAMP-dependent protein kinase catalytic subunit alpha&ids=P17612,,Q32P54,Q9H2Y0,Q9NRB4,Q9NRH9&cid=0&pid=1592)
GoogleScholar
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In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=cAMP-dependent protein kinase catalytic subunit alpha&ids=36055000)
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PKAC-alphaMore data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=cAMP-dependent protein kinase catalytic subunit alpha&ids=hsa:5566)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=cAMP-dependent protein kinase catalytic subunit alpha&ids=P17612,,Q32P54,Q9H2Y0,Q9NRB4,Q9NRH9&cid=0&pid=1592)
GoogleScholar
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In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=cAMP-dependent protein kinase catalytic subunit alpha&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50624682(CHEMBL5414047)
Affinity DataIC50: 18nMAssay Description:Inhibition of human GRK2More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)PDB[
3D Structure (crystal)](/rwd/bind/forward%5Fotherdbs.jsp?dbName=Jmol&title=%22Beta-adrenergic+receptor+kinase+1%22 AND %22BDBM50624682%22&ids=6U7C&monomerid=0&polymerid=p5264)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50173319(CHEMBL3809020 | US10023564, Example 11)
Affinity DataIC50: 20nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
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In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50173313(CHEMBL1738878)
Affinity DataIC50: 20nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
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In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50624686(CHEMBL5415336)
Affinity DataIC50: 20nMAssay Description:Inhibition of GRK5 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50260140(CHEMBL4090144)
Affinity DataIC50: 30nMAssay Description:Inhibition of human GRK2More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPurchasePC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)PDB[3D Structure (crystal)](/rwd/bind/forward%5Fotherdbs.jsp?dbName=Jmol&title=%22Beta-adrenergic+receptor+kinase+1%22 AND %22BDBM50260140%22&ids=5UKM&monomerid=0&polymerid=p5264)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50257350(CHEMBL1738877)
Affinity DataIC50: 30nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
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In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)PDB[3D Structure (crystal)](/rwd/bind/forward%5Fotherdbs.jsp?dbName=Jmol&title=%22Beta-adrenergic+receptor+kinase+1%22 AND %22BDBM50257350%22&ids=3PVU,5UUU&monomerid=0&polymerid=p5264)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 42nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM283996(US10023564, Example 22 | E22)
Affinity DataIC50: 160nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50529465(CHEMBL4464632)
Affinity DataIC50: 220nMAssay Description:Time dependent inhibition of GRK5 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoPurchasePC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50624684(CHEMBL5406336)
Affinity DataIC50: 236nMAssay Description:Inhibition of GRK2 (unknown origin) using CRRREEEEESAAA as substrate measured for 120 mins in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50624683(CHEMBL5412633)
Affinity DataIC50: 250nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50624683(CHEMBL5412633)
Affinity DataIC50: 260nMAssay Description:Inhibition of GRK5 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM283996(US10023564, Example 22 | E22)
Affinity DataIC50: 380nMAssay Description:Inhibition of GRK5 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50: 390nMAssay Description:Inhibition of GRK2 (unknown origin) using CRRREEEEESAAA as substrate measured for 120 mins in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
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In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50: 770nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPurchasePC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50624685(CHEMBL5398985)
Affinity DataIC50: 1.10E+3nMAssay Description:Time dependent inhibition of GRK5 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human GRK2More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPurchaseCHEMBLDrugBankKEGGPC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)PDB[3D Structure (crystal)](/rwd/bind/forward%5Fotherdbs.jsp?dbName=Jmol&title=%22Beta-adrenergic+receptor+kinase+1%22 AND %22BDBM22416%22&ids=3V5W&monomerid=0&polymerid=p5264)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50624685(CHEMBL5398985)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GRK5 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50265871(3-(2-(1-(2-(dimethylamino)acetyl)-6-methoxy-4,4-di...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of GRK2 (unknown origin) measured for 4 hrsMore data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoCHEMBLPC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM50246208(cid_274122 | CHEMBL487046 | 2-(3,4,5-trihydroxy-6-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoCHEMBLPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM27791(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50260140(CHEMBL4090144)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of C-terminal his6-tagged human GRK5More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoPurchasePC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
Ligand
BDBM27826(4-fluoro-2-[(2-{[2-methoxy-4-(1-propylpiperidin-4-...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Mus musculus)
West China Hospital
Curated by ChEMBL
Ligand
BDBM357857(US10214536, Amlexanox | Aphthasol)
Affinity DataIC50: 8.86E+3nMAssay Description:Inhibition of mouse GRK5More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:5578)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=Q8VEB1,,O70292,O70297&cid=0&pid=50001633)
GoogleScholar
Ligand InfoPurchasePC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetRhodopsin kinase GRK1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM27791(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of GRK1 (unknown origin)More data for this Ligand-Target Pair
Target Info[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Rhodopsin kinase GRK1&ids=hsa:6011)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Rhodopsin kinase GRK1&ids=Q15835,,Q53X14&cid=0&pid=50003773)
GoogleScholar
Ligand InfoPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Rhodopsin kinase GRK1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50265871(3-(2-(1-(2-(dimethylamino)acetyl)-6-methoxy-4,4-di...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoCHEMBLPC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetRhodopsin kinase GRK1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50260140(CHEMBL4090144)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of C-terminal his6-tagged human GRK1More data for this Ligand-Target Pair
Target Info[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Rhodopsin kinase GRK1&ids=hsa:6011)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Rhodopsin kinase GRK1&ids=Q15835,,Q53X14&cid=0&pid=50003773)
GoogleScholar
Ligand InfoPurchasePC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Rhodopsin kinase GRK1&ids=36055000)
TargetG protein-coupled receptor kinase 5(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal his6-tagged human GRK5More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=G protein-coupled receptor kinase 5&ids=hsa:2869)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=G protein-coupled receptor kinase 5&ids=P34947,,D3DRD0,Q5T059&cid=0&pid=50004461)
GoogleScholar
Ligand InfoPurchaseCHEMBLDrugBankKEGGPC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=G protein-coupled receptor kinase 5&ids=36055000)
TargetRhodopsin kinase GRK1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal his6-tagged human GRK1More data for this Ligand-Target Pair
Target Info[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Rhodopsin kinase GRK1&ids=hsa:6011)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Rhodopsin kinase GRK1&ids=Q15835,,Q53X14&cid=0&pid=50003773)
GoogleScholar
Ligand InfoPurchaseCHEMBLDrugBankKEGGPC cidPC sidPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Rhodopsin kinase GRK1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50173313(CHEMBL1738878)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetRhodopsin kinase GRK1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM27826(4-fluoro-2-[(2-{[2-methoxy-4-(1-propylpiperidin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK1 (unknown origin)More data for this Ligand-Target Pair
Target Info[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Rhodopsin kinase GRK1&ids=hsa:6011)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Rhodopsin kinase GRK1&ids=Q15835,,Q53X14&cid=0&pid=50003773)
GoogleScholar
Ligand InfoPC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Rhodopsin kinase GRK1&ids=36055000)
TargetRhodopsin kinase GRK1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50529465(CHEMBL4464632)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK1 (unknown origin)More data for this Ligand-Target Pair
Target Info[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Rhodopsin kinase GRK1&ids=hsa:6011)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Rhodopsin kinase GRK1&ids=Q15835,,Q53X14&cid=0&pid=50003773)
GoogleScholar
Ligand InfoPurchasePC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Rhodopsin kinase GRK1&ids=36055000)
TargetBeta-adrenergic receptor kinase 1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50529465(CHEMBL4464632)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDB[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Beta-adrenergic receptor kinase 1&ids=hsa:156)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Beta-adrenergic receptor kinase 1&ids=P25098,,B0ZBE1,Q13837,Q6GTT3&cid=0&pid=5264)
GoogleScholar
Ligand InfoPurchasePC cidPC sidSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Beta-adrenergic receptor kinase 1&ids=36055000)
TargetRhodopsin kinase GRK1(Human)
West China Hospital
Curated by ChEMBL
LigandBDBM50624685(CHEMBL5398985)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK1 (unknown origin)More data for this Ligand-Target Pair
Target Info[KEGG](/rwd/bind/forward%5Fotherdbs.jsp?dbName=KEGG&title=Rhodopsin kinase GRK1&ids=hsa:6011)
[UniProtKB/SwissProt](/rwd/bind/forward%5Fotherdbs.jsp?dbName=UniProt&title=Rhodopsin kinase GRK1&ids=Q15835,,Q53X14&cid=0&pid=50003773)
GoogleScholar
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
[PubMed](/rwd/bind/forward%5Fotherdbs.jsp?dbName=PubMed&title=Rhodopsin kinase GRK1&ids=36055000)