In malaria: The course of the disease …five related protozoan (single-celled) parasites: Plasmodium falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi. The most common worldwide is P. vivax. The deadliest is P. falciparum. In 2008 P. knowlesi, which was thought to infect primarily Old World monkeys and to occur only rarely in Read More
characteristics of parasites
In community ecology: Alternation among hosts …to another: the malarial parasite Plasmodium falciparum alternates between a final human host and an intermediate mosquito host by which the parasite is transferred from one person to another. The parasite uses the mosquito as a mobile hypodermic syringe. Examples of a similar kind of transmission between a final host… Read More
control by chloroquine
In chloroquine ovale, and P. falciparum as well as certain parasitic worms and amoebas. It is also used in the treatment of inflammatory rheumatic diseases, such as lupus erythematosus and rheumatoid arthritis. Read More
sensitivity to quinine
In quinine …strains of the malarial parasite Plasmodium falciparum developed resistance to the synthetic drugs, particularly the highly valued chloroquine. The parasite remained sensitive, however, to quinine, which had to be reinstated in various parts of the world as the drug of choice despite the side effects that sometimes occur when the… Read More
species of Plasmodium
In Plasmodium ovale (relatively uncommon), P. falciparum (producing the most severe symptoms), P. malariae, and P. knowlesi. There are several species that have been isolated from chimpanzees, including P. reichenowi and P. gaboni. P. falciparum, P. gaboni, and other species have been isolated from gorillas. Examples of parasites found in… Read More
work of Smith
In George P. Smith …such as those produced by Plasmodium falciparum, a parasite that causes malaria. For his discoveries, Smith was awarded the 2018 Nobel Prize in Chemistry, which he shared with American chemist Frances Arnold and British-born biochemist Sir Greg Winter. Read More
