Dihydrotestosterone | hormone | Britannica (original) (raw)

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male pattern baldness

• In baldness
  …reducing the body’s production of dihydrotestosterone, a powerful variant of testosterone that helps cause male pattern baldness.
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prostate cancer prevention

• In prostate cancer: Causes
  …of two active compounds—estradiol or dihydrotestosterone. Whereas estradiol promotes the growth of prostate cancer cells, dihydrotestosterone inhibits the programmed death (apoptosis) of those cells. Testosterone itself appears to play a central role in maintaining prostate cells and stimulating apoptosis when abnormal cells arise. However, the mechanism by which testosterone and…
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testosterone

• In testosterone
  …a more active androgen called dihydrotestosterone. Testosterone is converted to dihydrotestosterone in most tissues that are sensitive to androgens, including the testes, prostate gland, hair follicles, and muscles. Although testosterone itself has androgenic actions, its conversion to dihydrotestosterone is critical to the development of external genitalia in boys. Testosterone is…
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