Nicotinamide adenine dinucleotide phosphate | chemical compound | Britannica (original) (raw)
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genetic disease
In human genetic disease: Molecular oxygen …by a multicomponent enzyme called nicotine adenine dinucleotide phosphate (NADPH) oxidase. A defect in any of the components of this oxidase will lead to the absence of the respiratory burst, giving rise to the constant infections indicative of CGD. Before the discovery and clinical application of antibiotics, people born with… Read More
metabolic oxidation reactions
In nucleotide …along with the related compound nicotinamide adenine dinucleotide phosphate (NADP). These substances act as cofactors to certain enzymes. Read More
In metabolism: The phosphogluconate pathway …nicotine adenine dinucleotide phosphate (NADP+), a coenzyme similar to but not identical with NAD+. A second molecule of NADP+ is reduced as 6-phosphogluconate is further oxidized; the reaction is catalyzed by 6-phosphogluconate dehydrogenase [13]. The products of the reaction also include ribulose 5-phosphate and carbon dioxide. (The numbers at… Read More
photosynthesis
In photosynthesis: Overall reaction of photosynthesis of ATP and the electron-donor-reduced nicotine adenine dinucleotide phosphate (NADPH). During the dark stage, the ATP and NADPH formed in the light-capturing reactions are used to reduce carbon dioxide to organic carbon compounds. This assimilation of inorganic carbon into organic compounds is called carbon fixation. Read More
In photosynthesis: The Calvin-Benson cycle ATP and NADPH formed during the light reactions are utilized for key steps in this pathway and provide the energy and reducing equivalents (i.e., electrons) to drive the sequence in the direction shown. For each molecule of carbon dioxide that is fixed, two molecules of NADPH and… Read More
