Cellosaurus cell line NL20T-A (CVCL_3757) (original) (raw)
Cell line name
NL20T-A
Synonyms
NL20-TA; NL20TA
Accession
CVCL_3757
Resource Identification Initiative
To cite this cell line use: NL20T-A (RRID:CVCL_3757)
Comments
Population: Caucasian.
Characteristics: Tumorigenic. Established from a subcutaneous tumor in an athymic nude mouse inoculated with the parent cell line (PubMed=8521416).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: SNP array analysis.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin
Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy
Parent: CVCL_C5B5 (NL20T)
Sex of cell
Female
Age at sampling
20Y
Category
Transformed cell line
STR profile
Source(s): ATCC=CRL-2504
Markers:
| Amelogenin | X |
|---|---|
| CSF1PO | 11 |
| D2S1338 | 21,24 |
| D3S1358 | 14,17 |
| D5S818 | 12 |
| D7S820 | 12 |
| D8S1179 | 12,13 |
| D13S317 | 11,12 |
| D16S539 | 12 |
| D18S51 | 14 |
| D19S433 | 13,15.2 |
| D21S11 | 29,31.2 |
| FGA | 22,23 |
| Penta D | 9,11 |
| Penta E | 6,15,16 |
| TH01 | 6,7 |
| TPOX | 9,11 |
| vWA | 14,17 |
[ **Run an STR similarity search on this cell line**](/cellosaurus-str-search/?name=NL20T-A&Amelogenin=X&CSF1PO=11&D13S317=11,12&D16S539=12&D18S51=14&D19S433=13,15.2&D21S11=29,31.2&D2S1338=21,24&D3S1358=14,17&D5S818=12&D7S820=12&D8S1179=12,13&FGA=22,23&Penta D=9,11&Penta E=6,15,16&TH01=6,7&TPOX=9,11&vWA=14,17&)
Publications
PubMed=8521416
Schiller J.H., Bittner G.N.
Loss of the tumorigenic phenotype with in vitro, but not in vivo, passaging of a novel series of human bronchial epithelial cell lines: possible role of an alpha5/beta1-integrin-fibronectin interaction.
Cancer Res. 55:6215-6221(1995)
PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)
Cross-references
Cell line collections (Providers)
ATCC; CRL-2504
Cell line databases/resources
CLO; CLO_0008180
cancercelllines; CVCL_3757
Encyclopedic resources
Wikidata; Q54930687
Gene expression databases
GEO; GSM827477
Polymorphism and mutation databases
Progenetix; CVCL_3757
Entry history
Entry creation
04-Apr-2012
Last entry update
02-May-2024
Version number
16