Cellosaurus cell line T5-1 (CVCL_E839) (original) (raw)

Cell line name

T5-1

Synonyms

T5-1 (3.1.0); T51; T51 LCL; PGLC 33H(T5-1)

Accession

CVCL_E839

Secondary accession

CVCL_H270

Resource Identification Initiative

To cite this cell line use: T5-1 (RRID:CVCL_E839)

Comments

Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.

HLA typing

Source: IPD-IMGT/HLA=11419

Class I
HLA-A A*02:01:01:01
HLA-B B*08,27
Class II
HLA-DP DPA1*01:03:01

Disease

Infectious mononucleosis (NCIt: C34726)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_JA31 (L33-6-1)
Children:

Sex of cell

Female

Age at sampling

Age unspecified

Category

Transformed cell line

Publications

PubMed=4504337; DOI=10.1073/pnas.69.5.1244; PMCID=PMC426673
Koki Sato, Ronald S. Slesinski, John Walley Littlefield;
Chemical mutagenesis at the phosphoribosyltransferase locus in cultured human lymphoblasts.
Proc. Natl. Acad. Sci. U.S.A. 69:1244-1248(1972)

PubMed=4599625; DOI=10.1073/pnas.70.8.2401; PMCID=PMC433744
Stuart Holland Orkin, Philip D. Buchanan, William J. Yount, Howard Reisner, John Walley Littlefield;
Lambda-chain production in human lymphoblast-mouse fibroblast hybrids.
Proc. Natl. Acad. Sci. U.S.A. 70:2401-2405(1973)

PubMed=62390; DOI=10.1111/j.1365-3083.1976.tb03029.x
William J. Yount, Peter D. Utsinger, Lindsey M. Hutt-Fletcher, Philip D. Buchanan, Joseph H. Korn, C. Randall Fuller, Marshall J. Logue, Joseph S. Pagano;
Subpopulations of human lymphoblastoid cell lines. Correlation with the expression of surface receptors and content of Epstein-Barr virus genome.
Scand. J. Immunol. 5:795-810(1976)

PubMed=75508; DOI=10.1038/271459a0
Paul Gladstone, Donald A. Pious;
Stable variants affecting B cell alloantigens in human lymphoid cells.
Nature 271:459-461(1978)

Cross-references

Cell line collections (Providers)

ECACC; 94071434

Cell line databases/resources

dbMHC; 49031
IHW; IHW09284
IPD-IMGT/HLA; 11419

Encyclopedic resources

Wikidata; Q54971583

Experimental variables resources

EFO; EFO_0022350

Entry history

Entry creation

22-Oct-2012

Last entry update

19-Dec-2024

Version number

16