Cellosaurus cell line Sdhb-/- CL 7 (CVCL_HG13) (original) (raw)

Cell line name

Sdhb-/- CL 7

Synonyms

Sdhb -/- CL 7

Accession

CVCL_HG13

Resource Identification Initiative

To cite this cell line use: Sdhb-/- CL 7 (RRID:CVCL_HG13)

Comments

Knockout cell: Method=Cre/loxP; MGI; MGI:1914930; Sdhb.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.

Species of origin

Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6Ncr x 129S6/SvEvTac.

Hierarchy

Parent: CVCL_HG11 (Sdhb fl/fl)

Sex of cell

Male

Age at sampling

Blastocyst stage

Category

Transformed cell line

Publications

PubMed=26302408; DOI=10.1038/ncb3233; PMCID=PMC4591470
Simone Cardaci, Liang Zheng, Gillian MacKay, Niels J.F. van den Broek, Elaine D. MacKenzie, Colin Nixon, David Stevenson, Sergey Tumanov, Vinay Bulusu, Jurre J. Kamphorst, Alexei Vazquez, Stewart Fleming, Francesca Schiavi, Gabriela Kalna, Karen Blyth, Douglas Strathdee, Eyal Gottlieb; Show fewer authors
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Nat. Cell Biol. 17:1317-1326(2015)

Cross-references

Cell line collections (Providers)

CancerTools; 153293
Ximbio; 153293

Encyclopedic resources

Wikidata; Q54952717

Entry history

Entry creation

01-Dec-2016

Last entry update

29-Jun-2023

Version number