Cellosaurus cell line Q34 (CVCL_VS16) (original) (raw)

Cell line name

Q34

Accession

CVCL_VS16

Resource Identification Initiative

To cite this cell line use: Q34 (RRID:CVCL_VS16)

Comments

Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Met53Thr (c.158T>C); ClinVar=VCV001480737; Zygosity=Heterozygous (PubMed=12417717).
• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp108Asn (c.322G>A) (p.Arg122Gln, c.365G>A); ClinVar=VCV000216275; Zygosity=Heterozygous (PubMed=12417717).

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_VS15 ! Hmel-p16-2

Sex of cell

Female

Age at sampling

28Y

Category

Finite cell line

Publications

PubMed=12417717; DOI=10.1128/mcb.22.23.8135-8143.2002; PMCID=PMC134058
Thomas J. Huot, Janice Rowe, Mark Harland, Sarah Drayton, Sharon Brookes, Chandra Gooptu, Patricia Purkis, Mike Fried, Veronique Bataille, Eiji Hara, Julia A. Newton-Bishop, Gordon Peters;
Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts.
Mol. Cell. Biol. 22:8135-8143(2002)

Cross-references

Encyclopedic resources

Wikidata; Q98128734

Entry history

Entry creation

25-Feb-2019

Last entry update

19-Dec-2024

Version number

9