| Name |
Ciprofloxacin (JP18/USP/INN);Cipro (TN);Otiprio (TN) |
| Product |
|
| Generic |
CIPROFLOXACIN (Baxter Healthcare Corporation), CIPROFLOXACIN (Baxter Healthcare Corporation), CIPROFLOXACIN (Sagent Pharmaceuticals), CIPROFLOXACIN (Sagent Pharmaceuticals), CIPROFLOXACIN IN DEXTROSE (Hospira) |
| Formula |
C17H18FN3O3 |
| Exact mass |
331.1332 |
| Mol weight |
331.34 |
| Structure |
 |
| Simcomp |
|
| Class |
Antibacterial DG01550 Quinolone DG01549 FluoroquinoloneMetabolizing enzyme inhibitor DG01634 CYP1A2 inhibitor |
| Remark |
Same as: C05349Therapeutic category: 6241ATC code: J01MA02 S01AE03 S02AA15 S03AA07Chemical structure group: DG00617Product (DG00617): D00186<JP/US> D02216<JP/US> |
| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
| Disease |
Inhalational anthrax [DS:H00328]Plague [DS:H00297] |
| Target |
DNA gyrase [KO:K02469 K02470] |
| Interaction |
CYP inhibition: CYP1A2 [HSA:1544] |
| Structure map |
map07014 Quinolones |
| Other map |
map04976 Bile secretion |
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01M QUINOLONE ANTIBACTERIALS J01MA Fluoroquinolones J01MA02 Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN) <JP/US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01A ANTIINFECTIVES S01AE Fluoroquinolones S01AE03 Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN) <JP/US> S02 OTOLOGICALS S02A ANTIINFECTIVES S02AA Antiinfectives S02AA15 Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN) <JP/US> S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS S03A ANTIINFECTIVES S03AA Antiinfectives S03AA07 Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>USP drug classification [BR:br08302] Antibacterials Quinolones Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN) Ophthalmic Agents Ophthalmic Anti-Infectives Antibacterials, Ophthalmic Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN) Otic Agents Otic Anti-Infectives Ciprofloxacin D00186 Ciprofloxacin (JP18/USP/INN)Therapeutic category of drugs in Japan [BR:br08301] 6 Agents against pathologic organisms and parasites 62 Chemotherapeutics 624 Synthetic antibacterials 6241 Pyridonecarboxylic acids D00186 Ciprofloxacin (JP18/USP/INN)Drug groups [BR:br08330] Antibacterial DG01550 Quinolone DG01549 Fluoroquinolone DG00617 Ciprofloxacin D00186 Ciprofloxacin Metabolizing enzyme inhibitor DG01634 CYP1A2 inhibitor DG00617 Ciprofloxacin D00186 CiprofloxacinDrug classes [BR:br08332] Antibacterial DG01549 Fluoroquinolone D00186 CiprofloxacinAntimicrobials [BR:br08307] Antibacterials Nucleic acid synthesis inhibitor Fluoroquinolone D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00186 CiprofloxacinDrug metabolizing enzymes and transporters [br08309.html] Drug metabolizing enzymes D00186Drug groups [BR:br08330] Antibacterial DG01550 Quinolone DG01549 Fluoroquinolone DG00617 Ciprofloxacin Metabolizing enzyme inhibitor DG01634 CYP1A2 inhibitor DG00617 CiprofloxacinAntimicrobials abbreviations [BR:br08327] Antibacterials Nucleic acid synthesis inhibitor Fluoroquinolone DG00617 Ciprofloxacin |
| Other DBs |
CAS: 85721-33-1PubChem: 7847254ChEBI: 100241PDB-CCD: CPF[PDBj] LigandBox: D00186NIKKAJI: J21.732H |
| LinkDB |
|
| KCF data |
ATOM 24 1 C8y C 19.6700 -6.0900 2 C8y C 19.6700 -7.4900 3 C8x C 20.8600 -8.1900 4 C8y C 22.1200 -7.4900 5 C8y C 22.1200 -6.0900 6 C8x C 20.8600 -5.3900 7 N4y N 23.3100 -8.1900 8 C8x C 24.5000 -7.4900 9 C8y C 24.5000 -6.0900 10 C8y C 23.3100 -5.3900 11 N1y N 18.4800 -8.1900 12 C1x C 17.2900 -7.4900 13 C1x C 16.0300 -8.1900 14 N1x N 16.0300 -9.5900 15 C1x C 17.2200 -10.2900 16 C1x C 18.4800 -9.5900 17 X F 18.4800 -5.3900 18 O5x O 23.3100 -3.9900 19 C6a C 25.6900 -5.3900 20 O6a O 26.8800 -6.0900 21 O6a O 25.6900 -3.9900 22 C1y C 23.3100 -9.5900 23 C1x C 24.0100 -10.7800 24 C1x C 22.6100 -10.7800BOND 27 1 1 2 2 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 2 6 1 6 1 7 4 7 1 8 7 8 1 9 8 9 2 10 9 10 1 11 5 10 1 12 2 11 1 13 11 12 1 14 12 13 1 15 13 14 1 16 14 15 1 17 15 16 1 18 11 16 1 19 1 17 1 20 10 18 2 21 9 19 1 22 19 20 1 23 19 21 2 24 7 22 1 25 22 23 1 26 22 24 1 27 23 24 1 |
