| Name |
Prazepam (JP18/USAN/INN);Centrax (TN) |
| Formula |
C19H17ClN2O |
| Exact mass |
324.1029 |
| Mol weight |
324.80 |
| Structure |
 |
| Simcomp |
|
| Class |
Neuropsychiatric agent DG01567 GABA-A receptor agonist DG01914 Anxiolytics, benzodiazepine derivatives |
| Remark |
Same as: C07366ATC code: N05BA11 |
| Efficacy |
Sedative-hypnotic |
| Comment |
Benzodiazepine derivative |
| Target |
GABR [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192] |
| Pathway |
hsa04080 Neuroactive ligand-receptor interactionhsa04727 GABAergic synapse |
| Interaction |
|
| Structure map |
map07230 GABA-A receptor agonists/antagonists |
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] N NERVOUS SYSTEM N05 PSYCHOLEPTICS N05B ANXIOLYTICS N05BA Benzodiazepine derivatives N05BA11 Prazepam D00470 Prazepam (JP18/USAN/INN)Drug groups [BR:br08330] Neuropsychiatric agent DG01567 GABA-A receptor agonist D00470 Prazepam DG01914 Anxiolytics, benzodiazepine derivatives D00470 PrazepamTarget-based classification of drugs [BR:br08310] Ion channels Ligand-gated ion channels GABA (ionotropic) GABR D00470 Prazepam (JP18/USAN/INN)Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00470 Prazepam D00470 Prazepam tabletsNarcotics and psychotropics in Japan [br08308.html] Psychotropics by Cabinet order Article 3 (78 substances) D00470 |
| Other DBs |
CAS: 2955-38-6PubChem: 7847536ChEBI: 8362LigandBox: D00470NIKKAJI: J3.397I |
| LinkDB |
|
| KCF data |
ATOM 23 1 C2y C 18.4100 -14.9800 2 C8y C 17.5700 -13.8600 3 C8y C 17.9200 -12.5300 4 N1y N 19.1800 -11.9700 5 N2x N 19.8100 -14.9800 6 C5x C 20.4400 -12.6000 7 C1x C 20.7200 -13.9300 8 C8x C 16.8700 -11.5500 9 C8x C 15.5400 -11.9700 10 C8y C 15.1900 -13.3000 11 C8x C 16.2400 -14.2800 12 O5x O 21.4900 -11.6200 13 X Cl 13.8600 -13.7200 14 C8y C 17.7800 -16.2400 15 C8x C 16.3800 -16.2400 16 C1b C 19.1800 -10.5700 17 C1y C 20.3700 -9.8700 18 C8x C 15.6800 -17.4300 19 C8x C 16.3800 -18.6900 20 C8x C 17.7800 -18.6900 21 C8x C 18.4800 -17.4300 22 C1x C 22.0500 -9.8700 23 C1x C 21.2100 -8.4000BOND 26 1 3 4 1 2 1 5 2 3 4 6 1 4 2 3 1 5 5 7 1 6 1 2 1 7 6 7 1 8 3 8 2 9 8 9 1 10 9 10 2 11 10 11 1 12 2 11 2 13 6 12 2 14 10 13 1 15 1 14 1 16 14 15 1 17 4 16 1 18 16 17 1 19 15 18 2 20 18 19 1 21 19 20 2 22 20 21 1 23 14 21 2 24 17 22 1 25 17 23 1 26 22 23 1 |
