| Name |
Bisoprolol (JAN/USAN/INN) |
| Formula |
C18H31NO4 |
| Exact mass |
325.2253 |
| Mol weight |
325.44 |
| Structure |
 |
| Simcomp |
|
| Class |
Cardiovascular agent DG01466 Adrenergic receptor antagonist DG01464 beta-Adrenergic receptor antagonist (Beta blocker) DG01461 beta1-Adrenergic receptor antagonist DG01653 Antiarrhythmics DG01806 Class II antiarrhythmic agent DG03231 Antihypertensive |
| Remark |
Same as: C06852Therapeutic category: 2149ATC code: C07AB07Chemical structure group: DG00316Product (DG00316): D02342<JP> D00634<JP/US> |
| Efficacy |
Antihypertensive, beta1-Adrenergic receptor antagonist |
| Comment |
Propranolol derivative |
| Target |
ADRB1 [HSA:153] [KO:K04141] |
| Pathway |
hsa04020 Calcium signaling pathwayhsa04022 cGMP-PKG signaling pathwayhsa04024 cAMP signaling pathwayhsa04080 Neuroactive ligand-receptor interactionhsa04261 Adrenergic signaling in cardiomyocytes |
| Interaction |
|
| Structure map |
map07214 beta-Adrenergic receptor agonists/antagonists |
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] C CARDIOVASCULAR SYSTEM C07 BETA BLOCKING AGENTS C07A BETA BLOCKING AGENTS C07AB Beta blocking agents, selective C07AB07 Bisoprolol D02342 Bisoprolol (JAN/USAN/INN) USP drug classification [BR:br08302] Cardiovascular Agents Beta-adrenergic Blocking Agents Beta-1 Selective Bisoprolol D02342 Bisoprolol (JAN/USAN/INN)Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 21 Cardiovascular agents 214 Antihypertensives 2149 Others D02342 Bisoprolol (JAN/USAN/INN)Drug groups [BR:br08330] Cardiovascular agent DG01466 Adrenergic receptor antagonist DG01464 beta-Adrenergic receptor antagonist (Beta blocker) DG01461 beta1-Adrenergic receptor antagonist DG00316 Bisoprolol D02342 Bisoprolol DG01653 Antiarrhythmics DG01806 Class II antiarrhythmic agent DG00316 Bisoprolol D02342 Bisoprolol DG03231 Antihypertensive DG00316 Bisoprolol D02342 BisoprololDrug classes [BR:br08332] Cardiovascular agent DG03231 Antihypertensive D02342 Bisoprolol DG01653 Antiarrhythmics D02342 BisoprololTarget-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Adrenaline ADRB1 D02342 Bisoprolol (JAN/USAN/INN) New drug approvals in Japan [br08318.html] Drugs with new active ingredients D02342Drug groups [BR:br08330] Cardiovascular agent DG01466 Adrenergic receptor antagonist DG01464 beta-Adrenergic receptor antagonist (Beta blocker) DG01461 beta1-Adrenergic receptor antagonist DG00316 Bisoprolol DG01653 Antiarrhythmics DG01806 Class II antiarrhythmic agent DG00316 Bisoprolol DG03231 Antihypertensive DG00316 Bisoprolol |
| Other DBs |
CAS: 66722-44-9PubChem: 7849401ChEBI: 3127LigandBox: D02342NIKKAJI: J32.485J |
| LinkDB |
|
| KCF data |
ATOM 23 1 C8y C 22.1200 -14.8400 2 C8x C 23.3800 -15.5400 3 C8x C 20.9300 -15.5400 4 O2a O 22.1200 -13.4400 5 C8x C 23.3800 -16.9400 6 C8x C 20.9300 -16.9400 7 C1b C 23.3100 -12.7400 8 C8y C 22.1200 -17.6400 9 C1c C 24.5700 -13.4400 10 C1b C 22.1200 -19.0400 11 C1b C 25.7600 -12.7400 12 O1a O 24.5700 -14.8400 13 O2a O 20.9300 -19.7400 14 N1b N 26.9500 -13.4400 15 C1b C 19.7400 -18.9700 16 C1c C 28.2100 -12.7400 17 C1b C 18.4800 -19.7400 18 C1a C 29.4000 -13.4400 19 C1a C 28.2100 -11.2700 20 O2a O 17.2900 -18.9700 21 C1c C 16.1000 -19.6700 22 C1a C 14.8400 -18.9700 23 C1a C 16.1000 -21.1400BOND 23 1 1 2 1 2 1 3 2 3 1 4 1 4 2 5 2 5 3 6 1 6 4 7 1 7 5 8 1 8 7 9 1 9 8 10 1 10 9 11 1 11 9 12 1 12 10 13 1 13 11 14 1 14 13 15 1 15 14 16 1 16 15 17 1 17 16 18 1 18 16 19 1 19 17 20 1 20 20 21 1 21 21 22 1 22 21 23 1 23 6 8 2 |
