| Name |
Moperone (INN) |
| Formula |
C22H26FNO2 |
| Exact mass |
355.1948 |
| Mol weight |
355.44 |
| Structure |
 |
| Simcomp |
|
| Class |
Neuropsychiatric agent DG01478 Dopamine antagonist DG01474 Dopamine D2-receptor antagonist DG03200 Antipsychotic agent DG01940 Butyrophenone derivative |
| Remark |
ATC code: N05AD04Chemical structure group: DG00888 |
| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
| Comment |
Butyrophenone derivative |
| Target |
DRD2 [HSA:1813] [KO:K04145] |
| Pathway |
hsa04080 Neuroactive ligand-receptor interactionhsa04540 Gap junction |
| Interaction |
|
| Structure map |
map07031 Antipsychotics - butyrophenones |
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] N NERVOUS SYSTEM N05 PSYCHOLEPTICS N05A ANTIPSYCHOTICS N05AD Butyrophenone derivatives N05AD04 Moperone D02623 Moperone (INN)Drug groups [BR:br08330] Neuropsychiatric agent DG01478 Dopamine antagonist DG01474 Dopamine D2-receptor antagonist DG00888 Moperone D02623 Moperone DG03200 Antipsychotic agent DG01940 Butyrophenone derivative DG00888 Moperone D02623 MoperoneTarget-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Dopamine DRD2 D02623 Moperone (INN)Drug groups [BR:br08330] Neuropsychiatric agent DG01478 Dopamine antagonist DG01474 Dopamine D2-receptor antagonist DG00888 Moperone DG03200 Antipsychotic agent DG01940 Butyrophenone derivative DG00888 Moperone |
| Other DBs |
CAS: 1050-79-9PubChem: 17396793LigandBox: D02623NIKKAJI: J7.228A |
| LinkDB |
|
| KCF data |
ATOM 26 1 C1b C 19.8100 -17.5700 2 C1b C 21.0700 -16.8700 3 C1b C 22.2600 -17.5700 4 N1y N 23.4500 -16.8700 5 C1x C 23.4500 -15.4700 6 C1x C 24.6400 -17.5700 7 C1x C 24.6400 -14.7700 8 C1x C 25.8300 -16.8700 9 C1z C 25.8300 -15.4700 10 C8y C 27.0200 -14.7700 11 C8x C 27.0200 -13.3700 12 C8x C 28.2100 -15.4700 13 C8x C 28.2100 -12.6700 14 C8x C 29.4000 -14.7700 15 C8y C 29.4000 -13.4400 16 C1a C 30.5900 -12.6700 17 C5a C 18.6200 -16.8000 18 C8y C 17.3600 -17.5700 19 O5a O 18.6200 -15.4000 20 C8x C 17.3600 -18.9700 21 C8x C 16.1700 -19.6700 22 C8y C 14.9100 -18.9700 23 C8x C 14.9100 -17.5700 24 C8x C 16.1700 -16.8000 25 X F 13.6500 -19.6700 26 O1a O 27.0200 -16.1700BOND 28 1 9 10 1 2 10 11 1 3 10 12 2 4 11 13 2 5 12 14 1 6 13 15 1 7 15 16 1 8 8 9 1 9 14 15 2 10 1 17 1 11 1 2 1 12 17 18 1 13 2 3 1 14 17 19 2 15 3 4 1 16 4 5 1 17 4 6 1 18 5 7 1 19 6 8 1 20 18 20 1 21 20 21 2 22 21 22 1 23 22 23 2 24 23 24 1 25 24 18 2 26 7 9 1 27 22 25 1 28 9 26 1 |
