| Name |
Meclozine (BAN);Meclizine;Nevidoxine (TN) |
| Formula |
C25H27ClN2 |
| Exact mass |
390.1863 |
| Mol weight |
390.95 |
| Structure |
 |
| Simcomp |
|
| Class |
Anti-allergic agent DG01557 Histamine receptor antagonist DG01482 Histamine receptor H1 antagonist |
| Remark |
Same as: C07116ATC code: R06AE05Chemical structure group: DG01106Product (DG01106): D01317<US> |
| Efficacy |
Anti-emetic, H1 receptor antagonist |
| Target |
HRH1 [HSA:3269] [KO:K04149] |
| Pathway |
hsa04080 Neuroactive ligand-receptor interactionhsa04750 Inflammatory mediator regulation of TRP channels |
| Interaction |
|
| Structure map |
map07212 Histamine H1 receptor antagonists |
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] R RESPIRATORY SYSTEM R06 ANTIHISTAMINES FOR SYSTEMIC USE R06A ANTIHISTAMINES FOR SYSTEMIC USE R06AE Piperazine derivatives R06AE05 Meclozine D08163 Meclozine (BAN)Risk category of Japanese OTC drugs [BR:br08312] Second-class OTC drugs Inorganic and organic chemicals Meclizine hydrochloride D08163 Meclozine (BAN)Drug groups [BR:br08330] Anti-allergic agent DG01557 Histamine receptor antagonist DG01482 Histamine receptor H1 antagonist DG01106 Meclozine D08163 MeclozineTarget-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Histamine HRH1 D08163 Meclozine (BAN)Drug groups [BR:br08330] Anti-allergic agent DG01557 Histamine receptor antagonist DG01482 Histamine receptor H1 antagonist DG01106 Meclozine |
| Other DBs |
CAS: 569-65-3PubChem: 96024853ChEBI: 6709LigandBox: D08163NIKKAJI: J6.532C |
| LinkDB |
|
| KCF data |
ATOM 28 1 C8x C 20.5100 -21.4200 2 C8y C 20.5100 -22.8200 3 C8x C 21.7000 -23.5200 4 C8x C 22.9600 -22.8200 5 C8y C 22.9600 -21.4200 6 C8x C 21.7000 -20.7200 7 C8x C 25.3400 -22.8200 8 C8y C 25.3400 -21.4200 9 C1c C 24.1500 -20.7200 10 C8x C 26.6000 -23.5200 11 C8x C 27.7900 -22.8200 12 C8x C 27.7900 -21.4200 13 C8x C 26.6000 -20.7200 14 N1y N 24.1500 -19.3200 15 C1x C 25.3400 -18.6200 16 C1x C 25.3400 -17.2200 17 N1y N 24.1500 -16.5200 18 C1x C 22.9600 -17.2200 19 C1x C 22.9600 -18.6200 20 C1b C 24.1500 -15.1200 21 C8y C 25.3400 -14.4200 22 C8x C 26.5300 -15.1200 23 C8y C 27.7900 -14.4200 24 C8x C 27.7900 -13.0200 25 C8x C 26.6000 -12.3200 26 C8x C 25.3400 -13.0200 27 C1a C 28.9800 -15.1200 28 X Cl 19.3200 -23.5200BOND 31 1 1 2 2 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 2 6 1 6 1 7 7 8 1 8 8 9 1 9 5 9 1 10 7 10 2 11 10 11 1 12 11 12 2 13 12 13 1 14 8 13 2 15 9 14 1 16 14 15 1 17 15 16 1 18 16 17 1 19 17 18 1 20 18 19 1 21 14 19 1 22 17 20 1 23 20 21 1 24 21 22 2 25 22 23 1 26 23 24 2 27 24 25 1 28 25 26 2 29 21 26 1 30 23 27 1 31 2 28 1 |
