Name |
Pipotiazine (INN);Piportil (TN) |
Formula |
C24H33N3O3S2 |
Exact mass |
475.1963 |
Mol weight |
475.67 |
Structure |
![](https://www.kegg.jp/Fig/drug/D08385.gif) |
Class |
Neuropsychiatric agent DG03200 Antipsychotic agent DG01905 Phenothiazine antipsychotics |
Remark |
ATC code: N05AC04Chemical structure group: DG00884 |
Efficacy |
Antipsychotic, Neuroleptic |
Comment |
Phenothiazine derivative |
Target |
DRD2 [HSA:1813] [KO:K04145]DRD1 [HSA:1812] [KO:K04144]HTR2A [HSA:3356] [KO:K04157]HTR1A [HSA:3350] [KO:K04153] |
Pathway |
hsa04080 Neuroactive ligand-receptor interactionhsa04726 Serotonergic synapsehsa04728 Dopaminergic synapse |
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] N NERVOUS SYSTEM N05 PSYCHOLEPTICS N05A ANTIPSYCHOTICS N05AC Phenothiazines with piperidine structure N05AC04 Pipotiazine D08385 Pipotiazine (INN)Drug groups [BR:br08330] Neuropsychiatric agent DG03200 Antipsychotic agent DG01905 Phenothiazine antipsychotics DG00884 Pipotiazine D08385 PipotiazineTarget-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Dopamine DRD1 D08385 Pipotiazine (INN) DRD2 D08385 Pipotiazine (INN) Serotonin HTR1A D08385 Pipotiazine (INN) HTR2A D08385 Pipotiazine (INN)Drug groups [BR:br08330] Neuropsychiatric agent DG03200 Antipsychotic agent DG01905 Phenothiazine antipsychotics DG00884 Pipotiazine |
Other DBs |
CAS: 39860-99-6PubChem: 96025071LigandBox: D08385NIKKAJI: J16.029F |
LinkDB |
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KCF data |
ATOM 32 1 C8x C 14.2800 -22.4700 2 C8x C 15.4700 -21.7700 3 C8y C 15.4700 -20.3700 4 C8x C 14.2800 -19.6700 5 C8y C 13.0900 -21.7700 6 C8y C 13.0900 -20.3700 7 N1y N 11.9000 -19.6700 8 S2x S 11.9000 -22.4700 9 C8y C 10.7100 -21.7700 10 C8y C 10.7100 -20.3700 11 C8x C 9.4500 -19.6700 12 C8x C 8.2600 -20.3700 13 C8x C 8.2600 -21.7700 14 C8x C 9.4500 -22.4700 15 C1b C 11.9000 -18.2700 16 C1b C 13.0900 -17.5700 17 C1b C 13.0900 -16.2400 18 N1y N 14.2800 -15.5400 19 C1x C 15.4700 -16.1700 20 C1x C 16.6600 -15.5400 21 C1y C 16.6600 -14.1400 22 C1x C 15.4700 -13.4400 23 C1x C 14.2800 -14.1400 24 C1b C 17.8500 -13.4400 25 C1b C 19.1100 -14.1400 26 O1a O 20.3000 -13.4400 27 S4a S 16.7300 -19.6700 28 N1c N 17.9200 -20.3700 29 C1a C 19.1100 -19.6700 30 C1a C 17.9200 -21.7700 31 O3c O 17.7100 -18.6900 32 O3c O 15.6800 -18.6900BOND 35 1 23 18 1 2 1 2 2 3 21 24 1 4 2 3 1 5 24 25 1 6 9 10 2 7 25 26 1 8 10 11 1 9 11 12 2 10 12 13 1 11 13 14 2 12 14 9 1 13 3 27 1 14 5 6 2 15 27 28 1 16 7 15 1 17 28 29 1 18 6 7 1 19 28 30 1 20 15 16 1 21 27 31 2 22 7 10 1 23 27 32 2 24 16 17 1 25 9 8 1 26 17 18 1 27 8 5 1 28 3 4 2 29 4 6 1 30 5 1 1 31 18 19 1 32 19 20 1 33 20 21 1 34 21 22 1 35 22 23 1 |