Lovell Allan Jones, PhD - Texas A&M Health Science Center School of Public Health | LinkedIn (original) (raw)

Texas A&M Health Science Center School of Public Health

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Dr. Lovell A. Jones received his PhD in 1977 in the field of zoology with an emphasis in…

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Articles by Lovell Allan

A Thousand Points of Light - Linking Those Dots

I came across this today on my Facebook as a memories. This is one of the dots, or as President George H.

IF YOU ALWAYS DO WHAT YOU HAVE ALREADY DONE

In the early weeks of 2008, a report published by the American Medical Association brought discouraging news for…

Food for Thought - One's Continuing Legacy

It is amazing how one picture keeps popping up. In 1987, the Biennial Symposium on Minorities & Cancer was launched in…

HDEART & ITS GLOBAL LEGACY

In 2005, Eucharia Iwuanyanwu, approached me about her vision of addressing cancer in Nigeria. Through her, and her…

The Legacy of the Health Disparities/Equity Programs

As we continue to connect the dots for the HDEART Health Equity Scholars & Alumni (HHESA) Network stories about the…

Connecting the Dots - The People One Leaves Behind.

It is all about Connecting the Dots. Earlier this month I wrote a Lovell's Food for Thought - Connecting the Dots…

A Piece By Dr. Robert Robinson

This is something I felt I need to share. For many Americans, the speech by Michelle Obama the other day was one for…

Lovell's Food For Thought - Connecting the Dots

When I started this journey more than 50 years ago, little did I realize that I would be at this place in time. As with…

An Open Letter to Dr. Marybeth Gasman and America

Thanks Marybeth Gasman for using your privilege in a positive way to bring to light what many of us have been talking…

Contributions

Activity

Experience & Education

View Lovell Allan’s full experience

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Volunteer Experience

Texas Divsion of the American Cancer Society

Aug 1988 - Aug 1990 2 years 1 month
Civil Rights and Social Action
Focusing on addressing cancer disparities

UIC Leadership Team

Unity of Houston

Feb 2017 - Present7 years 10 months
Health
Addressing the needs of the community

Board Member

Unity of Houston

Mar 2019 - Mar 2022 3 years 1 month
Governing board regarding church activities

CANDO Houston

Civil Rights and Social Action
Addressing the Social Determinants of Health

Publications

Environmental Health Perspectives Aug 2005

Abstract
The neonatal mouse model has been a valuable tool in determining the long-term effects of early exposure to estrogenic agents in mammals. Using this model, we compared the effects of 2′,4′,6′-trichloro-4-biphenylol (OH-PCB-30) and 2′,3′,4′,5′-tetrachloro-4-biphenylol (OH-PCB-61) as prototype estrogenic hydroxylated PCBs (OH-PCBs) because they are reported to exhibit relatively high estrogenic activity both in vivo and in vitro. The purpose of this study was to examine the…
Abstract
The neonatal mouse model has been a valuable tool in determining the long-term effects of early exposure to estrogenic agents in mammals. Using this model, we compared the effects of 2′,4′,6′-trichloro-4-biphenylol (OH-PCB-30) and 2′,3′,4′,5′-tetrachloro-4-biphenylol (OH-PCB-61) as prototype estrogenic hydroxylated PCBs (OH-PCBs) because they are reported to exhibit relatively high estrogenic activity both in vivo and in vitro. The purpose of this study was to examine the relationship between estrogenicity and carcinogenicity of OH-PCB congeners. The OH-PCBs were tested individually and in combination to determine whether effects of combined OH-PCBs differed from those of these OH-PCBs alone. We evaluated the long-term effects of neonatal exposure to OH-PCBs with treatment doses that were based on the reported binding affinity of specific OH-PCB congeners to estrogen receptor α. BALB/cCrgl female mice were treated within 16 hr after birth by subcutaneous injections every 24 hr, for 5 days. The mice treated with OH-PCB-30 (200 μg/day) or 17β-estradiol (5 μg/day) showed similar increased incidences of cervicovaginal (CV) tract carcinomas (43% and 47%, respectively). In addition, when mice were treated with OH-PCBs as a mixture, a change in the type of CV tract tumor was observed, shifting from predominantly squamous cell carcinomas to adenosquamous cell carcinoma. From our results, we conclude that the individual OH-PCBs tested were estrogenic and tumorigenic in mice when exposed during development of the reproductive tract. These data support the hypothesis that mixtures may act differently and unexpectedly than do individual compounds.
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Clinical Cancer Research 7: 2984-2997, 2001. 2001

Projects

Dec 2006 - Jan 2007

Developed by the Ariel Foundation International, Dr. Jones and Dr. Ariel King led an educational summit for teens 13 to 25 in the country of Lesotho. Dynamic images of the summit, participants, delegation from the United States, and Lesotho educational team
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Co-Founder

Apr 1995 - Present

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