Hives and angioedema - Symptoms and causes (original) (raw)

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Overview

Hives — also known as urticaria (ur-tih-KAR-e-uh) — is a skin reaction that causes itchy welts that range in size from small spots to large blotches. Hives can be triggered by many situations and substances, including certain foods and medications.

Angioedema can arise with hives or alone. It causes swelling in the deeper layers of skin, often around the face and lips. Short-lived (acute) hives and angioedema are common. Most times, they are harmless, clear up within in a day and don't leave any lasting marks, even without treatment. Hives that last longer than six weeks are called chronic hives.

Hives and angioedema are usually treated with antihistamine medication. Angioedema can be life-threatening if swelling of the tongue or in the throat blocks the airway.

Symptoms

Hives

The welts associated with hives can be:

Most hives appear quickly and go away within 24 hours. This is known as acute hives. Chronic hives can last for months or years.

Angioedema

Angioedema is a reaction similar to hives that affects deeper layers of the skin. It can appear with hives or alone. Signs and symptoms include:

When to see a doctor

You can usually treat mild cases of hives or angioedema at home. See your health care provider if your symptoms continue for more than a few days.

If you think your hives or angioedema was caused by a known allergy to food or a medication, your symptoms may be an early sign of an anaphylactic reaction. Seek emergency care if you feel your tongue, lips, mouth or throat swelling or if you're having trouble breathing.

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Causes

For most people who experience acute hives and angioedema, the exact cause can't be identified. The conditions are sometimes caused by:

Risk factors

Hives and angioedema are common. You may be at increased risk of hives and angioedema if you:

Complications

Severe angioedema can be life-threatening if swelling of the tongue or in the throat blocks the airway.

Prevention

To lower your likelihood of experiencing hives or angioedema, take the following precautions:

Oct. 27, 2023

  1. AskMayoExpert. Urticaria. Mayo Clinic; 2020.
  2. Kang S, et al., eds. Urticaria and angioedema. In: Fitzpatrick's Dermatology. 9th ed. McGraw-Hill; 2019. https://accessmedicine.mhmedical.com. Accessed Aug. 29, 2019.
  3. Hives (urticaria). American College of Allergy, Asthma, and Immunology. http://acaai.org/allergies/types/skin-allergies/hives-urticaria. Accessed Aug. 4, 2021.
  4. Ferri FF. Urticaria. In: Ferri's Clinical Advisor 2022. Elsevier; 2022. https://www.clinicalkey.com. Accessed Aug. 4, 2021.
  5. Asero R. New-onset urticaria. https://www.uptodate.com/contents/search. Accessed Aug. 4, 2021.
  6. Zuraw B, et al. An overview of angioedema: Clinical features, diagnosis, and management. https://www.uptodate.com/contents/search. Accessed Aug. 4, 2021.
  7. Hives. American Academy of Dermatology. https://www.aad.org/public/diseases/a-z/hives-treatment. Accessed Aug. 4, 2021.
  8. Thompson DA. Hives. In: Adult Telephone Protocols: Office Version. 4th ed. American Academy of Pediatrics; 2018.
  9. Briggs JK. Hives. In: Triage Protocols for Aging Adults. Wolters Kluwer; 2019.
  10. Kelly AP, et al., eds. Drug eruptions. In: Taylor and Kelly's Dermatology for Skin of Color. 2nd ed. McGraw Hill; 2016. https://accessmedicine.mhmedical.com. Accessed Aug. 4, 2021.
  11. Zuraw B, et al. Hereditary angioedema: Acute treatment of angioedema attacks. https://www.uptodate.com/contents/search. Accessed Aug. 9, 2021.
  12. Kelly AP, et al. Biology of wounds and wound care. In: Taylor and Kelly's Dermatology for Skin of Color. 2nd ed. McGraw-Hill Education; 2016. Accessmedicine.mhmedical.com. Accessed May 27, 2021.

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