Definition of HYALURONIDASE (original) (raw)

: a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid

Examples of hyaluronidase in a Sentence

Recent Examples on the Web

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.

In these cases, dissolving the filler with hyaluronidase removes that puffiness entirely, without the need for surgery. —Kara Nesvig, Allure, 4 Aug. 2025 After allowing time for your lips to settle — typically a couple of weeks — a medical professional can reevaluate the symmetry, contour, and firmness of your lips and use hyaluronidase to dissolve some or all of the filler in a certain spot. —Carlos Wolf, Miami Herald, 11 July 2025 The hyaluronidase is then directly injected into the site of the hyaluronic acid dermal filler, and then the area is massaged. —Jackie Fields, People.com, 15 Jan. 2025 Giving them a better idea of where to insert the hyaluronidase. —Celeste Polanco, Essence, 13 Sep. 2024 How does Topilase compare to injectable hyaluronidase? —Jolene Edgar, Harper's BAZAAR, 23 Dec. 2022

Word History

Etymology

International Scientific Vocabulary, from hyaluronic (acid) + -idase (as in glucosidase)

First Known Use

1940, in the meaning defined above

Time Traveler

The first known use of hyaluronidase was in 1940

Browse Nearby Words

Cite this Entry

“Hyaluronidase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hyaluronidase. Accessed 15 May. 2026.

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