Mature proteins braced by a chaperone (original) (raw)

Molecular biology

Nature volume 539, pages 361–362 (2016)Cite this article

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Hsp70 chaperone molecules help other proteins to fold, and were thought to bind mainly to unfolded proteins. Single-molecule experiments now suggest that Hsp70s can also stabilize almost fully folded proteins. See Letter p.448

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Figure 1: Different roles of Hsp70s in protein folding.

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Author notes

  1. Elizabeth A. Craig is in the Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin 53706-1544, USA.

Authors and Affiliations

  1. Qinglian Liu is in the Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia 23298-0551, USA.,
    Qinglian Liu & Elizabeth A. Craig

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  1. Qinglian Liu
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  2. Elizabeth A. Craig
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Correspondence toQinglian Liu or Elizabeth A. Craig.

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Liu, Q., Craig, E. Mature proteins braced by a chaperone.Nature 539, 361–362 (2016). https://doi.org/10.1038/nature20470

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