CDK4 cyclin dependent kinase 4 [Homo sapiens (human)] - Gene (original) (raw)

Exon count:

8

Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (57747727..57752310, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (57716081..57720660, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (58141510..58146093, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in [Genomic regions, transcripts, and products](#geneGenomic regions, transcripts, and products) above.

Genomic

  1. NG_007484.2 RefSeqGene
    Range
    4935..9655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_490

mRNA and Protein(s)

  1. NM_000075.4NP_000066.1 cyclin-dependent kinase 4
    See identical proteins and their annotated locations for NP_000066.1
    Status: REVIEWED
    Source sequence(s)
    [AC025165, BC003644, BI832658, BQ773564](/nuccore/AC025165, BC003644, BI832658, BQ773564)
    Consensus CDS
    CCDS8953.1
    UniProtKB/Swiss-Prot
    B2R9A0, B4DNF9, O00576, P11802, Q6FG61
    Related
    ENSP00000257904.5, ENST00000257904.11
    Conserved Domains (1) summary
    cl21453
    Location:5 → 295
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly
    Range
    57747727..57752310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0
    Range
    57716081..57720660 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

These RefSeqs were suppressed for the cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links, or BLAST links (BLink), but may still be retrieved by clicking on their accession.version below.

  1. NM_052984.1: Suppressed sequence
    Description
    NM_052984.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.