Mus musculus sodium channel, voltage-gated, type VIII, alpha (Scn8a), - Nucleotide (original) (raw)

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Mus musculus sodium channel, voltage-gated, type VIII, alpha (Scn8a), transcript variant 2, mRNA

NCBI Reference Sequence: NM_011323.3

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Articles about the Scn8a gene

• Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy. [JCI Insight. 2024]
  Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy.
  Miralles RM, Boscia AR, Kittur S, Hanflink JC, Panchal PS, Yorek MS, Deutsch TCJ, Reever CM, Vundela SR, Wengert ER, et al. JCI Insight. 2024 Oct 22; 9(20). Epub 2024 Oct 22.
• Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy. [Neurobiol Dis. 2024]
  Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy.
  Neurobiol Dis. 2024 Sep; 199:106591. Epub 2024 Jul 3.
• Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6. [Sci Rep. 2024]
  Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6.
  Arratia LM, Bermudes-Contreras JD, Juarez-Monroy JA, Romero-Macías EA, Luna-Rojas JC, López-Hidalgo M, Vega AV, Zamorano-Carrillo A. Sci Rep. 2024 Mar 21; 14(1):6761. Epub 2024 Mar 21.

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Reference sequence information

• RefSeq alternative splicing
  See 12 reference mRNA sequence splice variants for the Scn8a gene.
• RefSeq protein product
  See the reference protein sequence for sodium channel protein type 8 subunit alpha isoform 2 (NP_035453.2).

More about the Scn8a gene

Related information

• Protein
  Protein sequence from Nucleotide coding region
• PubMed
  PubMed articles cited by Nucleotide sequence record
• Taxonomy
  Taxonomy sequences associated with Nucleotide record
• Annotated Genomic
  Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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  BioSystems
• CCDS
  Link to Consensus CDS
• Components (Core)
  Links to Core components
• Full text in PMC
  Free full text articles in PMC
• Functional Class
  Functional class of the sequence domain architecture
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  Link to related Genes
• OMIM
  OMIM records associated with Nucleotide sequence
• Probe
  Related Probe entry
• PubMed (RefSeq)
  Link to RefSeq PubMed articles
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• GEO Profiles
  GEO Profile records associated with Nucleotide record

LinkOut to external resources

• Ensembl [Ensembl]
  Ensembl
• Ensembl [Ensembl]
  Ensembl
• Ensembl [Ensembl]
  Ensembl
• reagent reviews [ExactAntigen/Labome]
  reagent reviews
  ExactAntigen/Labome
• reagents [ExactAntigen/Labome]
  reagents
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• GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
  GenScript latest version of gene cDNA ORF Clone
• Order TALEN/CRISPR clone [GeneCopoeia Inc.]
  Order TALEN/CRISPR clone
  GeneCopoeia Inc.
• Order full-length cDNA clone [GeneCopoeia Inc.]
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  GeneCopoeia Inc.
• Order qPCR primer [GeneCopoeia Inc.]
  Order qPCR primer
  GeneCopoeia Inc.
• UCSC Genome Browser [UCSC Genome Browser]
  UCSC Genome Browser

Recent activity

Finds sub-sequence or patterns in the sequence and highlights the matching region. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences.
More...