Cell biology of viruses that assemble along the biosynthetic pathway (original) (raw)

Abstract

In this review we discuss five groups of viruses that bud into, or assemble from, different compartments along the biosynthetic pathway. These are herpes-, rota-, corona-, bunya- and poxviruses. Our main emphasis will be on the virally-encoded membrane glycoproteins that are responsible for determining the site of virus assembly. In a number of cases these proteins have been well characterized and appear to serve as resident markers of the budding compartments. The assembly and dissemination of these viruses raises many questions of cell biological interest.

Keywords: biosynthetic pathway, intracellular budding viruses, membrane glycoproteins, virus assembly

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