THE OCCURRENCE OF MUCOID POLYSACCHARIDE IN HEMOLYTIC STREPTOCOCCI OF HUMAN ORIGIN (original) (raw)

• Journal List
• J Exp Med
• v.77(1); 1943 Jan 1
• PMC2135291

J Exp Med. 1943 Jan 1; 77(1): 21–28.

From the Department of Bacteriology, The University of Wisconsin Medical School, Madison

Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York

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Abstract

1. A rapid method for the roughly quantitative estimation of mucoid polysaccharide in hemolytic streptococci has been described. 2. Using this method, about 94 per cent of strains from moderate or severe streptococcal infections in man have been found to produce mucoid polysaccharide in greater or less amount. In a group of streptococci from normal throats only about 8 per cent produced this substance, all of the producers falling into Lancefield's group A. 3. Of the Lancefield group A strains from both normal and infected sources, 92 per cent showed the presence of mucoid polysaccharide in culture dilutions of 1:10 or higher. 4. The probable significance of the mucoid polysaccharide in streptococcal virulence is indicated.

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Selected References

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• Seastone CV. THE VIRULENCE OF GROUP C HEMOLYTIC STREPTOCOCCI OF ANIMAL ORIGIN. J Exp Med. 1939 Sep 30;70(4):361–378. [PMC free article] [PubMed] [Google Scholar]
• Meyer K, Chaffee E, Hobby GL, Dawson MH. HYALURONIDASES OF BACTERIAL AND ANIMAL ORIGIN. J Exp Med. 1941 Feb 28;73(3):309–326. [PMC free article] [PubMed] [Google Scholar]
• Hirst GK. THE EFFECT OF A POLYSACCHARIDE-SPLITTING ENZYME ON STREPTOCOCCAL INFECTION. J Exp Med. 1941 Mar 31;73(4):493–506. [PMC free article] [PubMed] [Google Scholar]
• Todd EW, Lancefield RC. VARIANTS OF HEMOLYTIC STREPTOCOCCI; THEIR RELATION TO TYPE-SPECIFIC SUBSTANCE, VIRULENCE, AND TOXIN. J Exp Med. 1928 Nov 30;48(6):751–767. [PMC free article] [PubMed] [Google Scholar]
• Lyons C, Ward HK. STUDIES ON THE HEMOLYTIC STREPTOCOCCUS OF HUMAN ORIGIN : II. OBSERVATIONS ON THE PROTECTIVE MECHANISM AGAINST THE VIRULENT VARIANTS. J Exp Med. 1935 Mar 31;61(4):531–543. [PMC free article] [PubMed] [Google Scholar]
• Seastone CV. Capsules in Young Cultures of Streptococcus hemolyticus. J Bacteriol. 1934 Nov;28(5):481–487. [PMC free article] [PubMed] [Google Scholar]

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