large conductance calcium- and voltage-dependent potassium channel alp - Protein (original) (raw)
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large conductance calcium- and voltage-dependent potassium channel alpha subunit [Homo sapiens]
GenBank: AAB65837.1
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Protein 3D Structure
- Crystal structure of the human BK channel gating ring L390P mutant
PDB: 6V5A
Source: Homo sapiens
Method: X-ray Diffraction
Resolution: 2 Å
Articles about the KCNMA1 gene
- Evaluation of four KCNMA1 channelopathy variants on BK channel current under Ca(V)1.2 activation. [Channels (Austin). 2024]
Evaluation of four KCNMA1 channelopathy variants on BK channel current under Ca(V)1.2 activation.
Dinsdale RL, Meredith AL. Channels (Austin). 2024 Dec; 18(1):2396346. Epub 2024 Sep 1. - Structural mapping of patient-associated KCNMA1 gene variants. [Biophys J. 2024]
Structural mapping of patient-associated KCNMA1 gene variants.
Moldenhauer HJ, Tammen K, Meredith AL. Biophys J. 2024 Jul 16; 123(14):1984-2000. Epub 2023 Dec 1. - Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models. [J Gen Physiol. 2023]
Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models.
Dinsdale RL, Roache CE, Meredith AL. J Gen Physiol. 2023 Nov 6; 155(11). Epub 2023 Sep 20.
Reference sequence information
- RefSeq genomic sequence
See the genomic reference sequence for the KCNMA1 gene (NG_012270.1). - RefSeq protein isoforms
See 102 reference sequence protein isoforms for the KCNMA1 gene.
More about the KCNMA1 gene
- This gene encodes the alpha subunit of calcium-activated BK channel. The encoded protein is involved in several physiological processes incl...
Also Known As: BKTM, CADEDS, IEG16, KC...
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- MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
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large conductance calcium- and voltage-dependent potassium channel alpha subunit [Homo sapiens]
gi|507922|gb|AAB65837.1|
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Finds sub-sequence or patterns in the sequence and highlights the matching region. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences.
More...
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