sodium channel, voltage gated, type VIII, alpha, isoform CRA_b [Homo s - Protein (original) (raw)
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Find regions of similarity between this sequence and other sequences using BLAST. - Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search. - Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... - Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More... - Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.
Articles about the SCN8A gene
- [Clinical features and genetic analysis of five children with epilepsies due to variants of SCN8A gene]. [Zhonghua Yi Xue Yi Chuan Xue Z...]
[Clinical features and genetic analysis of five children with epilepsies due to variants of SCN8A gene].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2024 Feb 10; 41(2):174-180. - Expanding the genotype-phenotype spectrum in SCN8A-related disorders. [BMC Neurol. 2024]
Expanding the genotype-phenotype spectrum in SCN8A-related disorders.
Hebbar M, Al-Taweel N, Gill I, Boelman C, Dean RA, Goodchild SJ, Mezeyova J, Shuart NG, Johnson JP Jr, Lee J, et al. BMC Neurol. 2024 Jan 17; 24(1):31. Epub 2024 Jan 17. - Clinical severity is correlated with age at seizure onset and biophysical properties of recurrent gain of function variants associated with SCN8A-related epilepsy. [Epilepsia. 2023]
Clinical severity is correlated with age at seizure onset and biophysical properties of recurrent gain of function variants associated with SCN8A-related epilepsy.
Chung KM, Hack J, Andrews J, Galindo-Kelly M, Schreiber J, Watkins J, Hammer MF. Epilepsia. 2023 Dec; 64(12):3365-3376. Epub 2023 Oct 12.
More about the SCN8A gene
Related information
- BioProject
Proteins related to BioProjects - Nucleotide
Nucleotide sequence from coding region - PubMed
PubMed articles cited by protein sequence record - Taxonomy
Taxonomy sequences associated with protein record - BioSystems
BioSystems - CDD Search Results
Display conserved domains within a protein - Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein - Conserved Domains (Full)
Link to conserved domains within a protein - Domain Relatives
Display proteins with similar conserved domain architecture - Full text in PMC
Free full text articles in PMC - Gene
Link to related Genes - Genome
Genome record encoding protein sequence - PubMed (Weighted)
Links to pubmed - Related Structures (List)
List of related structures
LinkOut to external resources
- reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome - reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
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Finds sub-sequence or patterns in the sequence and highlights the matching region. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences.
More...