RecName: Full=Progranulin; Short=PGRN; AltName: Full=Acrogranin; AltNa - Protein (original) (raw)
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RecName: Full=Progranulin; Short=PGRN; AltName: Full=Acrogranin; AltName: Full=Epithelin precursor; AltName: Full=Glycoprotein of 88 Kda; Short=GP88; Short=Glycoprotein 88; AltName: Full=Granulin precursor; AltName: Full=PC cell-derived growth factor; Short=PC...
UniProtKB/Swiss-Prot: P28799.2
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Articles about the GRN gene
- Neurofilaments and progranulin are related to atrophy in frontotemporal lobar degeneration - A transdiagnostic study cross-validating atrophy and fluid biomarkers. [Alzheimers Dement. 2024]
Neurofilaments and progranulin are related to atrophy in frontotemporal lobar degeneration - A transdiagnostic study cross-validating atrophy and fluid biomarkers.
Hüper L, Steinacker P, Polyakova M, Mueller K, Godulla J, Herzig S, Danek A, Engel A, Diehl-Schmid J, Classen J, et al. Alzheimers Dement. 2024 Jul; 20(7):4461-4475. Epub 2024 Jun 12. - A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors. [Alzheimers Res Ther. 2024]
A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors.
Swift IJ, Rademakers R, Finch N, Baker M, Ghidoni R, Benussi L, Binetti G, Rossi G, Synofzik M, Wilke C, et al. Alzheimers Res Ther. 2024 Mar 28; 16(1):66. Epub 2024 Mar 28. - Progranulin and neuropathological features of Alzheimer's disease: longitudinal study. [Aging Clin Exp Res. 2024]
Progranulin and neuropathological features of Alzheimer's disease: longitudinal study.
Aging Clin Exp Res. 2024 Mar 5; 36(1):55. Epub 2024 Mar 5.
Reference sequence information
- RefSeq genomic sequence
See the genomic reference sequence for the GRN gene (NG_007886.1). - RefSeq protein
See the reference protein sequence for progranulin precursor (NP_002078.1).
More about the GRN gene
Related information
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PubMed articles cited by protein sequence record - Taxonomy
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LinkOut to external resources
- Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository - P28799 [Domain Mapping of Disease Mut...]
P28799
Domain Mapping of Disease Mutations - Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System - Reactome [Reactome]
Reactome - reagents [ExactAntigen/Labome]
reagents
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reagent reviews
ExactAntigen/Labome
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- RecName: Full=Progranulin; Short=PGRN; AltName: Full=Acrogranin; AltName: Full=E...
RecName: Full=Progranulin; Short=PGRN; AltName: Full=Acrogranin; AltName: Full=Epithelin precursor; AltName: Full=Glycoprotein of 88 Kda; Short=GP88; Short=Glycoprotein 88; AltName: Full=Granulin precursor; AltName: Full=PC cell-derived growth factor; Short=PCDGF; AltName: Full=Proepithelin; Short=PEPI; Contains: RecName: Full=Paragranulin; Contains: RecName: Full=Granulin-1; AltName: Full=Granulin G; Contains: RecName: Full=Granulin-2; AltName: Full=Granulin F; Contains: RecName: Full=Granulin-3; AltName: Full=Epithelin-2; AltName: Full=Granulin B; Contains: RecName: Full=Granulin-4; AltName: Full=Epithelin-1; AltName: Full=Granulin A; Contains: RecName: Full=Granulin-5; AltName: Full=Granulin C; Contains: RecName: Full=Granulin-6; AltName: Full=Granulin D; Contains: RecName: Full=Granulin-7; AltName: Full=Granulin E; Flags: Precursor
gi|77416865|sp|P28799.2|GRN_HUMAN
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Finds sub-sequence or patterns in the sequence and highlights the matching region. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences.
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