RecName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase; Short - Protein (original) (raw)
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RecName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase; Short=Acid cholesteryl ester hydrolase; Short=LAL; AltName: Full=Cholesteryl esterase; AltName: Full=Diacylglycerol lipase; AltName: Full=Lipase A; AltName: Full=Sterol esterase; AltName: Full=Tr...
UniProtKB/Swiss-Prot: P38571.2
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Protein 3D Structure
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Crystal Structure of a human Lysosome Resident Glycoprotein, Lysosomal Acid Lipase, and its Implications in Cholesteryl Ester Storage Disease (CESD)
PDB: 6V7N
Source: Homo sapiens
Method: X-ray Diffraction
Resolution: 2.62 Å
Articles about the LIPA gene
- Pedigree Analysis of Nonclassical Cholesteryl Ester Storage Disease with Dominant Inheritance in a LIPA I378T Heterozygous Carrier. [Dig Dis Sci. 2024]
Pedigree Analysis of Nonclassical Cholesteryl Ester Storage Disease with Dominant Inheritance in a LIPA I378T Heterozygous Carrier.
Dig Dis Sci. 2024 Jun; 69(6):2109-2122. Epub 2024 Apr 2. - Prevalence of p.G87V and p.Gln298=Variations in LIPA Gene Within Middle Eastern Population Living Around Los Angeles. [Genet Test Mol Biomarkers. 2023]
Prevalence of p.G87V and p.Gln298=Variations in LIPA Gene Within Middle Eastern Population Living Around Los Angeles.
Jackson J, Farajzadeh J, Turner R, Yukutake K, Baghdasaryan E, Denis ES, Barseghyan T, Herrera P, Begaj S, Pietruszka M, et al. Genet Test Mol Biomarkers. 2023 Oct; 27(10):319-324. - Is lysosomal acid lipase activity associated with the presence and severity of coronary artery disease? [Herz. 2024]
Is lysosomal acid lipase activity associated with the presence and severity of coronary artery disease?
Kızıltunç E, Gökalp S, Biberoğlu G, Yalçın Y, Cihan B, Öktem RM, İnci A, Tümer L, Yalçın MR, Abacı A. Herz. 2024 Feb; 49(1):75-80. Epub 2023 Aug 1.
More about the LIPA gene
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PubMed articles cited by protein sequence record - Taxonomy
Taxonomy sequences associated with protein record - BioAssay by Target (Summary)
BioAssay by Target (Summary) - BioSystems
BioSystems - CDD Search Results
Display conserved domains within a protein - Conserved Domains (Concise)
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Display proteins with similar conserved domain architecture - Full text in PMC
Free full text articles in PMC - Gene
Link to related Genes - Identical Structures
3D structures for identical protein sequences - OMIM
OMIM records associated with protein sequence - Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq) - PubMed (Weighted)
Links to pubmed - Related Structures (List)
List of related structures
LinkOut to external resources
- P38571 [Domain Mapping of Disease Mut...]
P38571
Domain Mapping of Disease Mutations - Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System - Reactome [Reactome]
Reactome - reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome - reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
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Finds sub-sequence or patterns in the sequence and highlights the matching region. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences.
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