Risk of overweight among adolescents who were breastfed as infants - PubMed (original) (raw)
Risk of overweight among adolescents who were breastfed as infants
M W Gillman et al. JAMA. 2001.
Abstract
Context: Overweight during adolescence predicts short- and long-term morbidity as well as obesity in adulthood. The prevalence of overweight among adolescents is high and continues to increase. Physiological and behavioral mechanisms and preliminary epidemiologic data suggest that breastfeeding could lower the risk of subsequent obesity in adolescence.
Objective: To examine the extent to which overweight status among adolescents is associated with the type of infant feeding (breast milk vs infant formula) and duration of breastfeeding.
Design, setting, and subjects: Survey of 8186 girls and 7155 boys, aged 9 to 14 years, who are participants in the Growing Up Today Study, a nationwide cohort study of diet, activity, and growth. In the fall of 1996 we mailed a questionnaire to each of the subjects, and in the spring of 1997, we mailed a supplemental questionnaire to their mothers, who are participants in the Nurses' Health Study II.
Main outcome measure: Overweight status defined as body mass index exceeding the 95th percentile for age and sex from US national data.
Results: In the first 6 months of life, 9553 subjects (62%) were only or mostly fed breast milk, and 4744 (31%) were only or mostly fed infant formula. A total of 7186 subjects (48%) were breastfed for at least 7 months while 4613 (31%) were breastfed for 3 months or less. At ages 9 to 14 years, 404 girls (5%) and 635 boys (9%) were overweight. Among subjects who had been only or mostly fed breast milk, compared with those only or mostly fed formula, the odds ratio (OR) for being overweight was 0.78 (95% confidence interval [CI], 0.66-0.91), after adjustment for age, sex, sexual maturity, energy intake, time watching television, physical activity, mother's body mass index, and other variables reflecting social, economic, and lifestyle factors. Compared with subjects who had been breastfed for 3 months or less, those who had been breastfed for at least 7 months had an adjusted OR for being overweight of 0.80 (95% CI, 0.67-0.96). Timing of introduction of solid foods, infant formula, or cow's milk was not related to risk of being overweight.
Conclusion: Infants who were fed breast milk more than infant formula, or who were breastfed for longer periods, had a lower risk of being overweight during older childhood and adolescence.
Comment in
- Breastfeeding may help prevent childhood overweight.
Dietz WH. Dietz WH. JAMA. 2001 May 16;285(19):2506-7. doi: 10.1001/jama.285.19.2506. JAMA. 2001. PMID: 11368704 No abstract available. - Breastfeeding and risk of overweight.
Poothullil JM. Poothullil JM. JAMA. 2001 Sep 26;286(12):1448; author reply 1449-50. doi: 10.1001/jama.286.12.1448. JAMA. 2001. PMID: 11572729 No abstract available. - Breastfeeding and risk of overweight.
Poulton R, Williams S. Poulton R, et al. JAMA. 2001 Sep 26;286(12):1449-50. JAMA. 2001. PMID: 11572730 No abstract available.
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