Honey with high levels of antioxidants can provide protection to healthy human subjects - PubMed (original) (raw)
Clinical Trial
. 2003 Mar 12;51(6):1732-5.
doi: 10.1021/jf025928k.
Affiliations
- PMID: 12617614
- DOI: 10.1021/jf025928k
Clinical Trial
Honey with high levels of antioxidants can provide protection to healthy human subjects
Derek D Schramm et al. J Agric Food Chem. 2003.
Abstract
Free radicals and reactive oxygen species (ROS) have been implicated in contributing to the processes of aging and disease. Humans protect themselves from these damaging compounds, in part, by absorbing antioxidants from high-antioxidant foods. This report describes the effects of consuming 1.5 g/kg body weight of corn syrup or buckwheat honey on the antioxidant and reducing capacities of plasma in healthy human adults. The corn syrup treatment contained 0.21 +/- 0.06 mg of phenolic antioxidants per gram, and the two buckwheat honey treatments contained 0.79 +/- 0.02 and 1.71 +/- 0.21 mg of phenolic antioxidants per gram. Following consumption of the two honey treatments, plasma total-phenolic content increased (P < 0.05) as did plasma antioxidant and reducing capacities (P < 0.05). These data support the concept that phenolic antioxidants from processed honey are bioavailable, and that they increase antioxidant activity of plasma. It can be speculated that these compounds may augment defenses against oxidative stress and that they might be able to protect humans from oxidative stress. Given that the average sweetener intake by humans is estimated to be in excess of 70 kg per year, the substitution of honey in some foods for traditional sweeteners could result in an enhanced antioxidant defense system in healthy adults.
Similar articles
- Buckwheat honey increases serum antioxidant capacity in humans.
Gheldof N, Wang XH, Engeseth NJ. Gheldof N, et al. J Agric Food Chem. 2003 Feb 26;51(5):1500-5. doi: 10.1021/jf025897t. J Agric Food Chem. 2003. PMID: 12590505 - Total antioxidant content of alternatives to refined sugar.
Phillips KM, Carlsen MH, Blomhoff R. Phillips KM, et al. J Am Diet Assoc. 2009 Jan;109(1):64-71. doi: 10.1016/j.jada.2008.10.014. J Am Diet Assoc. 2009. PMID: 19103324 - Tualang honey has higher phenolic content and greater radical scavenging activity compared with other honey sources.
Kishore RK, Halim AS, Syazana MS, Sirajudeen KN. Kishore RK, et al. Nutr Res. 2011 Apr;31(4):322-5. doi: 10.1016/j.nutres.2011.03.001. Epub 2011 Apr 13. Nutr Res. 2011. PMID: 21530807 - Bioavailability and antioxidant effects of olive oil phenolic compounds in humans: a review.
Fitó M, de la Torre R, Farré-Albaladejo M, Khymenetz O, Marrugat J, Covas MI. Fitó M, et al. Ann Ist Super Sanita. 2007;43(4):375-81. Ann Ist Super Sanita. 2007. PMID: 18209271 Review. - Menopause: a review on the role of oxygen stress and favorable effects of dietary antioxidants.
Miquel J, Ramírez-Boscá A, Ramírez-Bosca JV, Alperi JD. Miquel J, et al. Arch Gerontol Geriatr. 2006 May-Jun;42(3):289-306. doi: 10.1016/j.archger.2005.08.005. Epub 2006 Jan 26. Arch Gerontol Geriatr. 2006. PMID: 16442644 Review.
Cited by
- Nutraceutical values of natural honey and its contribution to human health and wealth.
Ajibola A, Chamunorwa JP, Erlwanger KH. Ajibola A, et al. Nutr Metab (Lond). 2012 Jun 20;9:61. doi: 10.1186/1743-7075-9-61. Nutr Metab (Lond). 2012. PMID: 22716101 Free PMC article. - Antioxidant activities of some monofloral honey types produced across Minas Gerais (Brazil).
Pena Júnior DS, Almeida CA, Santos MCF, Fonseca PHV, Menezes EV, de Melo Junior AF, Brandão MM, de Oliveira DA, Souza LF, Silva JC, Royo VA. Pena Júnior DS, et al. PLoS One. 2022 Jan 19;17(1):e0262038. doi: 10.1371/journal.pone.0262038. eCollection 2022. PLoS One. 2022. PMID: 35045085 Free PMC article. - Effectiveness of forest honey ( Apis dorsata) as therapy for ovarian failure causing malnutrition.
Safitri E, Purnobasuki H, Purnama MTE, Chhetri S. Safitri E, et al. F1000Res. 2022 Oct 20;11:512. doi: 10.12688/f1000research.110660.2. eCollection 2022. F1000Res. 2022. PMID: 37767071 Free PMC article. - Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).
Hegazi AG, Abd El-Hady FK. Hegazi AG, et al. Evid Based Complement Alternat Med. 2009 Mar;6(1):113-21. doi: 10.1093/ecam/nem071. Epub 2007 Oct 18. Evid Based Complement Alternat Med. 2009. PMID: 18955249 Free PMC article. - Zero flow global ischemia-induced injuries in rat heart are attenuated by natural honey.
Najafi M, Zahednezhad F, Samadzadeh M, Vaez H. Najafi M, et al. Adv Pharm Bull. 2012;2(2):165-71. doi: 10.5681/apb.2012.025. Epub 2012 Jun 25. Adv Pharm Bull. 2012. PMID: 24312788 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical