Cortical sites critical for speech discrimination in normal and impaired listeners - PubMed (original) (raw)

Comparative Study

Cortical sites critical for speech discrimination in normal and impaired listeners

Dana F Boatman et al. J Neurosci. 2005.

Abstract

We used statistical modeling to investigate variability in the cortical auditory representations of 24 normal-hearing epilepsy patients undergoing electrocortical stimulation mapping (ESM). Patients were identified as normal or impaired listeners based on recognition accuracy for acoustically filtered words used to simulate everyday listening conditions. The experimental ESM task was a binary (same-different) auditory syllable discrimination paradigm that both listener groups performed accurately at baseline. Template mixture modeling of speech discrimination deficits during ESM showed larger and more variable cortical distributions for impaired listeners than normal listeners, despite comparable behavioral performances. These results demonstrate that individual differences in speech recognition abilities are reflected in the underlying cortical representations.

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Figures

Figure 1.

Figure 1.

Individual probability contours of sites associated with ESM auditory speech discrimination deficits in normal listeners (A) and impaired listeners (B). Black dots represent sites where speech discrimination was impaired; gray lines identify sites where speech discrimination remained intact. Yellow contours, 0.05 ≤ p < 0.10; orange contours, 0.10 ≤ _p_ < 0.20; red contours, _p_ > 0.20, where p is the probability that a site is associated with a deficit.

Figure 2.

Figure 2.

Population probability densities for the distribution of auditory speech discrimination deficits in normal listeners (A) and impaired listeners (B). Black dots represent sites where auditory speech discrimination was impaired; gray lines identify sites where speech discrimination was intact. Yellow contours, 0.05 ≤ p < 0.10; orange contours, 0.10 ≤ _p_ < 0.20; red contours, _p_ > 0.20, where p is the probability that a site is associated with a deficit.

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