Social defeat: risk factor for schizophrenia? - PubMed (original) (raw)

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Social defeat: risk factor for schizophrenia?

Jean-Paul Selten et al. Br J Psychiatry. 2005 Aug.

Abstract

The hypothesis that chronic and long-term experience of 'social defeat' may increase the risk for schizophrenia is proposed. This increased risk may result from sensitisation of the mesolimbic dopamine system and/or increased baseline activity of this system. Data supporting the social defeat hypothesis are presented.

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