Metabolic syndrome in people with schizophrenia: a review - PubMed (original) (raw)
Metabolic syndrome in people with schizophrenia: a review
Marc DE Hert et al. World Psychiatry. 2009 Feb.
Erratum in
- Erratum.
[No authors listed] [No authors listed] World Psychiatry. 2011 Feb;10(1):78. World Psychiatry. 2011. PMID: 21399733 Free PMC article.
Abstract
Metabolic syndrome and other cardiovascular risk factors are highly prevalent in people with schizophrenia. Patients are at risk for premature mortality and overall have limited access to physical health care. In part these cardio-metabolic risk factors are attributable to unhealthy lifestyle, including poor diet and sedentary behaviour. But over recent years it has become apparent that antipsychotic agents can have a negative impact on some of the modifiable risk factors. The psychiatrist needs to be aware of the potential metabolic side effects of antipsychotic medication and to include them in the risk/benefit assessment when choosing a specific antipsychotic. He should also be responsible for the implementation of the necessary screening assessments and referral for treatment of any physical illness. Multidisciplinary assessment of psychiatric and medical conditions is needed. The somatic treatments offered to people with severe and enduring mental illness should be at par with general health care in the non-psychiatrically ill population.
Keywords: Metabolic syndrome; antipsychotics; schizophrenia.
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References
- Brown S. Excess mortality of schizophrenia. A meta-analysis. Br J Psychiatry. 1997;171:502–508. - PubMed
- Brown S, Inskip H, Barraclough B. Causes of the excess mortality of schizophrenia. Br J Psychiatry. 2000;177:212–217. - PubMed
- Capasso RM, Lineberry TW, Bostwick JM. Mortality in schizophrenia and schizoaffective disorder: an Olmsted County, Minnesota cohort: 1950-2005. Schizophr Res. 2008;98:287–294. - PubMed
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