Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective - PubMed (original) (raw)
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Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective
Paul McVeigh et al. Microbes Infect. 2012 Apr.
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Abstract
Fasciola hepatica is a food-borne parasite of animals and humans. It secretes a large family of cysteine peptidases, termed cathepsins, that are important virulence factors. Here, we discuss how advances in molecular technologies have helped to probe the function of liver fluke cathepsins, and consider how evolving systems/molecular biology approaches can continue to inform our understanding of these important parasite enzymes.
Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.