A modified COMS plaque for iris melanoma - PubMed (original) (raw)

Case Reports

A modified COMS plaque for iris melanoma

Daniel J Scanderbeg et al. J Contemp Brachytherapy. 2011 Sep.

Abstract

Melanoma of the iris is a rare condition compared to posterior ocular tumors and in this case report we present a 51-year-old female patient with diffuse iris melanoma. Traditional COMS (Collaborative Ocular Melanoma Study) plaques are used at our institution for radiation therapy, so a novel modification of the traditional plaque was required to allow better conformance with placement on the cornea. The usual silastic insert was machined to dimensions in compliance with the cornea, placed without incident, and treatment delivered with excellent patient tolerance of the modified plaque.

Keywords: COMS; brachytherapy; eye plaque; iris melanoma.

PubMed Disclaimer

Figures

Fig. 1

Fig. 1

Photograph comparing the patient's normal eye versus that with diffuse iris melanoma. A) Darkening of the iris to blackbrown color in iris with some extension to cornea. B) Patient's normal eye

Fig. 2

Fig. 2

Schematic diagram of insert (left) and picture showing machined indentation (arrow) to accommodate cornea curvature

Fig. 3

Fig. 3

Surgery with plaque positioned directly on the cornea

References

    1. Marigo FA, Finger PT. Anterior segment tumors: current concepts and innovations. Surv Ophthalmol. 2003;48:569–593. -PubMed
    1. Jensen OA. Malignant melanomas of the human uvea. Recent follow-up of cases in Denmark, 1943-1952. Acta Ophthalmol (Copenh) 1970;48:1113–1128. -PubMed
    1. Shields CL, Shields JA, Materin M, et al. Iris melanoma: risk factors for metastasis in 169 consecutive patients. Ophthalmology. 2001;108:172–178. -PubMed
    1. Shields CL, Shields JA, De Potter P, et al. Treatment of non-resectable malignant iris tumors with custom designed plaque radiotherapy. Br J Ophthalmol. 1995;79:306–312. -PMC -PubMed
    1. Shields CL, Naseripour M, Shields JA, et al. Custom-designed plaque radiotherapy for non-resectable iris melanoma in 38 patients: Tumor control and ocular complications. Am J Ophthalmol. 2003;135:648–656. -PubMed

Publication types

LinkOut - more resources