Cardiovascular disease in COPD: mechanisms - PubMed (original) (raw)

Review

. 2013 Mar;143(3):798-807.

doi: 10.1378/chest.12-0938.

Affiliations

• PMID: 23460157
• DOI: 10.1378/chest.12-0938

Review

Cardiovascular disease in COPD: mechanisms

John D Maclay et al. Chest. 2013 Mar.

Abstract

It is now well established that cardiovascular disease contributes significantly to both morbidity and mortality in COPD. Shared risk factors for cardiovascular disease and COPD, such as smoking, low socioeconomic class, and a sedentary lifestyle contribute to the natural history of each of these conditions. However, it is now apparent that alternative, novel mechanisms are involved in the pathogenesis of cardiovascular disease, and these may play an important role in driving the increased cardiovascular risk associated with COPD. In this article, we discuss the potential mechanisms that link COPD to an increased risk of cardiovascular disease.

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Comment in

• Brain natriuretic peptide measurement in patients with COPD and cardiovascular disease.
  Kheir F, Salerno DA. Kheir F, et al. Chest. 2013 Sep;144(3):1081. doi: 10.1378/chest.13-0948. Chest. 2013. PMID: 24008964 No abstract available.
• Response.
  Maclay JD, MacNee W. Maclay JD, et al. Chest. 2013 Sep;144(3):1081-1082. doi: 10.1378/chest.13-1352. Chest. 2013. PMID: 24008965 No abstract available.

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