Skeletal muscle fatigue and decreased efficiency: two sides of the same coin? - PubMed (original) (raw)
Review
Skeletal muscle fatigue and decreased efficiency: two sides of the same coin?
Bruno Grassi et al. Exerc Sport Sci Rev. 2015 Apr.
Abstract
During high-intensity submaximal exercise, muscle fatigue and decreased efficiency are intertwined closely, and each contributes to exercise intolerance. Fatigue and muscle inefficiency share common mechanisms, for example, decreased "metabolic stability," muscle metabolite accumulation, decreased free energy of adenosine triphosphate breakdown, limited O2 or substrate availability, increased glycolysis, pH disturbance, increased muscle temperature, reactive oxygen species production, and altered motor unit recruitment patterns.
Comment in
- The critical power framework provides novel insights into fatigue mechanisms.
Poole DC, Barstow TJ. Poole DC, et al. Exerc Sport Sci Rev. 2015 Apr;43(2):65-6. doi: 10.1249/JES.0000000000000045. Exerc Sport Sci Rev. 2015. PMID: 25688764 Free PMC article. No abstract available.