Ethnopharmacologic investigation of ginger (Zingiber officinale) - PubMed (original) (raw)

Ethnopharmacologic investigation of ginger (Zingiber officinale)

N Mascolo et al. J Ethnopharmacol. 1989 Nov.

Abstract

An ethanolic extract of the rhizomes of Zingiber officinale was investigated for anti-inflammatory, analgesic, antipyretic, antimicrobial and hypoglycaemic activities. In rats, the extract reduced carrageenan-induced paw swelling and yeast-induced fever but was ineffective in suppressing the writhing induced by intraperitoneal acetic acid. The extract produced blood glucose lowering in rabbits. The growth of both Gram-positive and Gram-negative bacteria was significantly inhibited. A dose-dependent inhibition of prostaglandin release effect was observed using rat peritoneal leucocytes.

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