Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015) - PubMed (original) (raw)

Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015)

Angela A Hwang et al. Small. 2015 Oct.

Abstract

On page 5066, J. I. Zink, M. A. Horwitz, and co-workers use confocal microscopy to demonstrate the avid uptake of RITC-labeled mesoporous silica nanoparticles loaded with the anti-tuberculosis drug isoniazid (shown here in red) by human macrophages (nuclei stained blue with DAPI) infected with GFP-expressing Mycobacterium tuberculosis (shown here in green).

Keywords: drug delivery; mesoporous silica; mesoporous silica nanoparticles; multifunctional nanoparticles; tuberculosis.

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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