Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus - PubMed (original) (raw)

Review

Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus

A H Kissebah et al. Diabetes Metab Rev. 1989 Mar.

Abstract

Our studies support the view that body fat distribution and the accompanying metabolic abnormalities could be exacerabated by variability in the androgenic/estrogenic balance. Sensitivity to the androgenic milieu might be initiated by an early developmental aberration in sexual dimorphism. The possible direct and indirect sites of interaction between androgenic activity and the abnormal metabolic pathways in upper body obesity are summarized in Figure 19.

PubMed Disclaimer

Similar articles

• The role of androgens in metabolism, obesity, and diabetes in males and females.
  Navarro G, Allard C, Xu W, Mauvais-Jarvis F. Navarro G, et al. Obesity (Silver Spring). 2015 Apr;23(4):713-9. doi: 10.1002/oby.21033. Epub 2015 Mar 6. Obesity (Silver Spring). 2015. PMID: 25755205 Free PMC article. Review.
• The effects of physical training on insulin secretion and effectiveness and on glucose metabolism in obesity and type 2 (non-insulin-dependent) diabetes mellitus.
  Krotkiewski M, Lönnroth P, Mandroukas K, Wroblewski Z, Rebuffé-Scrive M, Holm G, Smith U, Björntorp P. Krotkiewski M, et al. Diabetologia. 1985 Dec;28(12):881-90. doi: 10.1007/BF00703130. Diabetologia. 1985. PMID: 3912243
• Insulin resistance, insulin deficiency and the pathogenesis of diabetes mellitus.
  Ferrannini E. Ferrannini E. Clin Physiol. 1986 Aug;6(4):311-7. doi: 10.1111/j.1475-097x.1986.tb00236.x. Clin Physiol. 1986. PMID: 3527530 Review. No abstract available.

Cited by

• Obesity, inflammation, and depression in adolescents.
  McLachlan C, Shelton R, Li L. McLachlan C, et al. Front Psychiatry. 2023 Sep 28;14:1221709. doi: 10.3389/fpsyt.2023.1221709. eCollection 2023. Front Psychiatry. 2023. PMID: 37840796 Free PMC article.
• Sex discrepancy in establishing mouse visceral obesity model induced by high-fat diet.
  Peng C, Miao Z, Wang Y, Cheng R, Shen X, He F. Peng C, et al. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023 Feb 25;52(1):117-125. doi: 10.3724/zdxbyxb-2022-0339. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023. PMID: 37283125 Free PMC article. Chinese, English.
• Combination of Pancreastatin inhibitor PSTi8 with metformin inhibits Fetuin-A in type 2 diabetic mice.
  Singh P, Garg R, Goand UK, Riyazuddin M, Reza MI, Syed AA, Gupta AP, Husain A, Gayen JR. Singh P, et al. Heliyon. 2020 Oct 3;6(10):e05133. doi: 10.1016/j.heliyon.2020.e05133. eCollection 2020 Oct. Heliyon. 2020. PMID: 33033766 Free PMC article.
• Abdominal Obesity, Adipokines and Non-communicable Diseases.
  Dhawan D, Sharma S. Dhawan D, et al. J Steroid Biochem Mol Biol. 2020 Oct;203:105737. doi: 10.1016/j.jsbmb.2020.105737. Epub 2020 Aug 18. J Steroid Biochem Mol Biol. 2020. PMID: 32818561 Free PMC article. Review.
• The Association between Adult Weight Gain and Insulin Resistance at Middle Age: Mediation by Visceral Fat and Liver Fat.
  Verkouter I, Noordam R, le Cessie S, van Dam RM, Lamb HJ, Rosendaal FR, van Heemst D, de Mutsert R. Verkouter I, et al. J Clin Med. 2019 Sep 28;8(10):1559. doi: 10.3390/jcm8101559. J Clin Med. 2019. PMID: 31569345 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Wiley

• Medical

  • MedlinePlus Health Information