Coronary artery calcium score and CT angiography in asymptomatic elderly patients with high pretest probability for coronary artery disease - PubMed (original) (raw)

Coronary artery calcium score and CT angiography in asymptomatic elderly patients with high pretest probability for coronary artery disease

Amir Imanzadeh et al. Jpn J Radiol. 2016 Feb.

Abstract

Purpose: To evaluate the role of coronary artery calcium scoring (CACS) and/or coronary CT angiography (CCTA) in asymptomatic elderly patients with high pretest probability for coronary artery disease (CAD).

Materials and methods: Forty-eight consecutive asymptomatic elderly (>65 years) subjects who had a high pretest probability and underwent CACS/CCTA were included. Each CCTA was evaluated for adequacy for assessment of coronary stenosis. Significant stenosis (>50% diameter narrowing) was assessed on evaluable CT images and by invasive catheter angiography (ICA).

Results: All subjects were men with mean CACS of 880 ± 1779. Among those with low (0-99), intermediate (100-399), and high (400-999) CACS, ICA-verified significant stenosis was present in 8% (1/13), 23% (2/13), and 67% (8/12), respectively. Among those with very high CACS (≥ 1000) (n = 10), 90% of CCTAs were not evaluable for stenosis.

Conclusion: In asymptomatic elderly subjects with high pretest probability, CACS followed by CCTA may be considered for those with intermediate to high CACS.

Keywords: Coronary CT angiography; Coronary artery calcium scoring; Coronary artery disease; Elderly.

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