Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field - PubMed (original) (raw)

. 2020 May;101(5):917-923.

doi: 10.1016/j.apmr.2020.01.007. Epub 2020 Feb 5.

Michael L Boninger 2, Laura J Miller 3, Luis Alvarez 4, Tomoki Aoyama 5, Marzia Bedoni 6, Kelley Ann Brix 7, Carmelo Chisari 8, George Christ 9, Christopher L Dearth 10, Trevor A Dyson-Hudson 11, Christopher H Evans 12, Stephen M Goldman 10, Kenton Gregory 13, Alice Gualerzi 6, Joseph Hart 14, Akira Ito 5, Hiroshi Kuroki 5, M Terry Loghmani 15, David L Mack 16, Gerard A Malanga 11, Linda Noble-Haeusslein 17, Paul Pasquina 4, Joseph A Roche 18, Lloyd Rose 19, Martin J Stoddart 20, Junichi Tajino 5, Carmen Terzic 12, Kimberly S Topp 21, William R Wagner 22, Stuart J Warden 23, Steven L Wolf 24, Hua Xie 13, Thomas A Rando 25, Fabrisia Ambrosio 26

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Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field

Nick J Willett et al. Arch Phys Med Rehabil. 2020 May.

Abstract

The growing field of regenerative rehabilitation has great potential to improve clinical outcomes for individuals with disabilities. However, the science to elucidate the specific biological underpinnings of regenerative rehabilitation-based approaches is still in its infancy and critical questions regarding clinical translation and implementation still exist. In a recent roundtable discussion from International Consortium for Regenerative Rehabilitation stakeholders, key challenges to progress in the field were identified. The goal of this article is to summarize those discussions and to initiate a broader discussion among clinicians and scientists across the fields of regenerative medicine and rehabilitation science to ultimately progress regenerative rehabilitation from an emerging field to an established interdisciplinary one. Strategies and case studies from consortium institutions-including interdisciplinary research centers, formalized courses, degree programs, international symposia, and collaborative grants-are presented. We propose that these strategic directions have the potential to engage and train clinical practitioners and basic scientists, transform clinical practice, and, ultimately, optimize patient outcomes.

Keywords: Regenerative medicine; Rehabilitation; Tissue engineering.

Published by Elsevier Inc.

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Figures

Fig 1

Fig 1

Number of publications by year in the regenerative rehabilitation field. Data from Web of Science search for publications using the terms “Regenerative medicine” AND Rehabilitation; OR “Regenerative Rehabilitation;” OR “Tissue Engineering” AND Rehabilitation (performed on March 6, 2020).

References

    1. U.S. Food and Drug Administration. Framework for the regulation of regenerative medicine products. Available at: https://www.fda.gov/vaccines-blood-biologics/cellular-gene-therapy-produ.... Accessed December 1, 2019.
    1. Kelly Scientific Publications. Global regenerative medicine market analysis & forecast to 2023: stem cells, tissue engineering, biobanking & CAR-T industries; 2019. Available at: https://kellysci.com/shop/kelly-scientific-reports/global-regenerative-m.... Accessed December 1, 2019.
    1. U.S. National Library of Medicine. Keyword search “Stem Cells”. Available at: https://clinicaltrials.gov/. Accessed April 26, 2019.
    1. Turner L, Knoepfler P. Selling stem cells in the USA: assessing the direct-to-consumer industry. Cell Stem Cell 2016;19:154–7. -PubMed
    1. Katzmarzyk PT, Janssen I. The economic costs associated with physical inactivity and obesity in Canada: an update. Can J Appl Physiol 2004;29:90–115. -PubMed

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