Multi-Organ Failure in a Patient With Diabetes due to COVID-19 With Clear Lungs - PubMed (original) (raw)

Case Reports

Multi-Organ Failure in a Patient With Diabetes due to COVID-19 With Clear Lungs

Sohaip Kabashneh et al. Cureus. 2020.

Abstract

The pandemic of coronavirus disease 2019 has emerged in late 2019 infecting millions of people worldwide. Diabetes mellitus (DM) has been associated with severe illness and mortality mainly due to acute respiratory distress syndrome. We report a case of a middle-aged man with DM and COVID-19 who developed seizure and altered mental status, found to have diabetic ketoacidosis (DKA), acute kidney injury, hypovolemic shock, and hyperammonemia all contributing to metabolic encephalopathy. He was admitted to the ICU and subsequently intubated for airway protection; with appropriate management his condition improved and was successfully extubated. The patient had no lung involvement throughout the illness. We report this case to highlight that COVID-19 can lead to multi-organ failure in patients with DM even in the absence of lung involvement which all physicians should be mindful of.

Keywords: coronavirus disease (covid-19); metabolic encephalopathy; multiorgan failure; severe diabetic ketoacidosis.

Copyright © 2020, Kabashneh et al.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1

Figure 1. Chest X-ray is unremarkable for infiltrates.

References

    1. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China. Wu Z, McGoogan JM. JAMA. 2020;323:1239. -PubMed
    1. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Zhou F, Yu T, Du R, et al. Lancet. 2020;395:1054. -PMC -PubMed
    1. Severe outcomes among patients with coronavirus disease 2019 (COVID-19) — United States, February 12-March 16, 2020. Bialek S, Boundy E, Bowen V, et al. Morbidity Mortality Weekly Rep. 2020;69:343–346. -PMC -PubMed
    1. Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Yang J, Lin S, Ji X, et al. Acta Diabetol. 2009;47:193–199. -PMC -PubMed
    1. Comorbidities and multi-organ injuries in the treatment of COVID-19. Wang T, Du Z, Zhu F, et al. Lancet. 2020;395:0. -PMC -PubMed

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