Noncontrast Pediatric Brain Perfusion: Arterial Spin Labeling and Intravoxel Incoherent Motion - PubMed (original) (raw)

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Noncontrast Pediatric Brain Perfusion: Arterial Spin Labeling and Intravoxel Incoherent Motion

Danny J J Wang et al. Magn Reson Imaging Clin N Am. 2021 Nov.

Abstract

Noncontrast magnetic resonance imaging techniques for measuring brain perfusion include arterial spin labeling (ASL) and intravoxel incoherent motion (IVIM). These techniques provide noninvasive and repeatable assessment of cerebral blood flow or cerebral blood volume without the need for intravenous contrast. This article discusses the technical aspects of ASL and IVIM with a focus on normal physiologic variations, technical parameters, and artifacts. Multiple pediatric clinical applications are presented, including tumors, stroke, vasculopathy, vascular malformations, epilepsy, migraine, trauma, and inflammation.

Keywords: ASL; Arterial spin labeling; Cerebral blood flow; Cerebral blood volume; Diffusion; IVIM; Intravoxel incoherent motion; Perfusion.

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Conflict of interest statement

Disclosure D.J.J. Wang is a shareholder of Translational MRI, LLC. D.L. Bihan, R. Krishnamurthy, and M. Smith have no disclosures. M-L. Ho is a principal investigator on the Radiological Society of North America (RSNA) Research Scholar Grant, Society for Pediatric Radiology (SPR) Pilot Award, and American Society of Head and Neck Radiology (ASHNR) William N. Hanafee Award, for work unrelated to this article.

Noncontrast Pediatric Brain Perfusion: Arterial Spin Labeling and Intravoxel Incoherent Motion - PubMed (original) (raw)