A Conversation on an Effective, Straightforward, Quantitative Approach to the Outpatient Use of Insulin - PubMed (original) (raw)

. 2022 Spring;35(2):179-189.

doi: 10.2337/ds21-0001. Epub 2022 Jan 10.

Affiliations

A Conversation on an Effective, Straightforward, Quantitative Approach to the Outpatient Use of Insulin

Mayer B Davidson. Diabetes Spectr. 2022 Spring.

Abstract

For primary care providers, using insulin can present challenges that can be met by a straightforward approach using the following principles. Depending on when it is injected, each component of the insulin regimen has a maximal effect on a specific period of the 24-hour cycle (e.g., overnight, morning, afternoon, or evening). The glucose pattern in that period determines whether the dose of that component of the insulin regimen requires adjusting. Regarding which insulin types and insulin regimens to use, human insulin (NPH and regular) is as effective as analog insulins, and a two-injection intensified insulin regimen is as effective as a four-injection regimen.

© 2022 by the American Diabetes Association.

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Figures

Figure 1

Figure 1

Flow diagram describing the initiation and dose adjustments of U-500 regular insulin. TDD, total daily dose.

References

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