Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19 - PubMed (original) (raw)
. 2023 Feb 9;12(1):29-35.
doi: 10.1093/jpids/piac113.
Ashley M Price 2, Samantha M Olson 2, Margaret M Newhams 3, Pia S Pannaraj 4, Aline B Maddux 5, Natasha B Halasa 6, Katherine E Bline 7, Melissa A Cameron 8, Stephanie P Schwartz 9, Tracie C Walker 9, Katherine Irby 10, Kathleen Chiotos 11, Ryan A Nofziger 12, Elizabeth H Mack 13, Laura Smallcomb 14, Tamara T Bradford 15, Satoshi Kamidani 16, Keiko M Tarquinio 17, Natalie Z Cvijanovich 18, Jennifer E Schuster 19, Samina S Bhumbra 20, Emily R Levy 21, Charlotte V Hobbs 22, Melissa L Cullimore 23, Bria M Coates 24, Sabrina M Heidemann 25, Shira J Gertz 26, Michele Kong 27, Heidi R Flori 28, Mary A Staat 29, Matt S Zinter 30, Janet R Hume 31, Brandon M Chatani 32, Mary G Gaspers 33, Mia Maamari 34, Adrienne G Randolph 3 35, Manish M Patel 2, Julie A Boom 1
Affiliations
- PMID: 36309873
- PMCID: PMC9620352
- DOI: 10.1093/jpids/piac113
Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19
Leila C Sahni et al. J Pediatric Infect Dis Soc. 2023.
Abstract
Background: Pfizer-BioNTech COVID-19 vaccine received emergency use authorization for persons ≥ 16 years in December 2020 and for adolescents 12-15 years in May 2021. Despite the clear benefits and favorable safety profile, vaccine uptake in adolescents has been suboptimal. We sought to assess factors associated with COVID-19 non-vaccination in adolescents 12-18 years of age.
Methods: Between June 1, 2021 and April 29, 2022, we assessed factors associated with COVID-19 non-vaccination in hospitalized adolescents ages 12-18 years enrolled in the Overcoming COVID-19 vaccine effectiveness network. Demographic characteristics and clinical information were captured through parent interviews and/or electronic medical record abstraction; COVID-19 vaccination was assessed through documented sources. We assessed associations between receipt of the COVID-19 vaccine and demographic and clinical factors using univariate and multivariable logistic regression and estimated adjusted odds ratios (aOR) for each factor associated with non-vaccination.
Results: Among 1665 hospitalized adolescents without COVID-19, 56% were unvaccinated. Unvaccinated adolescents were younger (median age 15.1 years vs. 15.4 years, p < .01) and resided in areas with higher social vulnerability index (SVI) scores (median 0.6 vs 0.5, p < .001) than vaccinated adolescents. Residence in the Midwest [aOR 2.60 (95% CI: 1.80, 3.79)] or South [aOR 2.49 (95% CI: 1.77, 3.54)] US census regions, rarely or never receiving influenza vaccine [aOR 5.31 (95% CI: 3.81, 7.47)], and rarely or never taking precautions against COVID-19 [aOR 3.17 (95% CI: 1.94, 5.31)] were associated with non-vaccination against COVID-19.
Conclusions: Efforts to increase COVID-19 vaccination of adolescents should focus on persons with geographic, socioeconomic, and medical risk factors associated with non-vaccination.
Keywords: COVID-19 vaccine; adolescent; risk factors.
© The Author(s) 2022. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.