Proceedings of the 2022 NHLBI and OASH state of the science in transfusion medicine symposium - PubMed (original) (raw)

. 2023 May;63(5):1074-1091.

doi: 10.1111/trf.17296. Epub 2023 Apr 2.

Evan M Bloch 3, Barbara J Bryant 4 5, Angelo D'Alessandro 6, Meghan Delaney 7, Ruchika Goel 8, Eldad A Hod 9, Cassandra D Josephson 3 10, Louis M Katz 11, Yvette M Miller 12, Merlyn H Sayers 13 14, Jansen N Seheult 15, Darrell J Triulzi 16, James Berger 17, Shimian Zou 18, Benyam Hailu 18, Simone A Glynn 18, Nareg H Roubinian 1 2 19

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Proceedings of the 2022 NHLBI and OASH state of the science in transfusion medicine symposium

Brian Custer et al. Transfusion. 2023 May.

Abstract

Background: State of the Science (SoS) meetings are used to define and highlight important unanswered scientific questions. The National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, and the Office of the Assistant Secretary for Health (OASH), Department of Health and Human Services held a virtual SoS in transfusion medicine (TM) symposium.

Study design and methods: In advance of the symposium, six multidisciplinary working groups (WG) convened to define research priorities in the areas of: blood donors and the supply, optimizing transfusion outcomes for recipients, emerging infections, mechanistic aspects of components and transfusion, new computational methods in transfusion science, and impact of health disparities on donors and recipients. The overall objective was to identify key basic, translational, and clinical research questions that will help to increase and diversify the volunteer donor pool, ensure safe and effective transfusion strategies for recipients, and identify which blood products from which donors best meet the clinical needs of specific recipient populations.

Results: On August 29-30, 2022, over 400 researchers, clinicians, industry experts, government officials, community members, and patient advocates discussed the research priorities presented by each WG. Dialogue focused on the five highest priority research areas identified by each WG and included the rationale, proposed methodological approaches, feasibility, and barriers for success.

Discussion: This report summarizes the key ideas and research priorities identified during the NHLBI/OASH SoS in TM symposium. The report highlights major gaps in our current knowledge and provides a road map for TM research.

© 2023 The Authors. Transfusion published by Wiley Periodicals LLC on behalf of AABB. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.

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References

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