Transcatheter Tricuspid Valve Replacement for Recurrent Tricuspid Regurgitation After Tricuspid Transcatheter Edge-to-Edge Repair - PubMed (original) (raw)

Case Reports

Transcatheter Tricuspid Valve Replacement for Recurrent Tricuspid Regurgitation After Tricuspid Transcatheter Edge-to-Edge Repair

Denizhan Ozdemir et al. JACC Case Rep. 2025.

Abstract

Background: It is currently unknown whether tricuspid valve replacement with EVOQUE is feasible after tricuspid transcatheter edge-to-edge repair.

Case summary: An 81-year-old patient with a complex history of multivalvular heart disease, previously treated with surgical and catheter approaches, presented to our center with symptomatic recurrent tricuspid regurgitation despite maximally tolerated medical therapy and previous tricuspid transcatheter edge-to-edge repair (T-TEER) with 2 TriClips. A multidisciplinary heart team determined that patient was high-risk for tricuspid surgery due to age, comorbidities, and previous sternotomy. Multimodality imaging revealed no anatomical contraindications for transcatheter tricuspid valve replacement (TTVR); however, due to the patient's history of appropriate antitachycardia therapies, implantable cardioverter-defibrillator lead removal and leadless pacemaker implantation were performed, enabling safe and successful transcatheter tricuspid valve replacement in the presence of the prior T-TEER device.

Discussion: Although limited to individual case reports, TTVR with EVOQUE may be feasible for select patients at experienced centers.

Keywords: tricuspid valve; valve repair; valve replacement.

Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.

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Conflict of interest statement

Funding Support and Author Disclosures Dr Moody Makar has been a consultant to Abbott Vascular, Boston Scientific, and Edwards Lifesciences. Dr Jilaihawi has received institutional grants for clinical research in Pi-Cardia, holds equity and has served on the scientific advisory board for DASI Simulations, and has been a consultant to Edwards Lifesciences and Medtronic. Dr Gupta has received grant support from the National Heart, Lung, and Blood Institute (1R56HL175516-01) and is a co-founder of Heartbeat Health, Inc (a telehealth cardiology company), and icardio.ai (an artificial intelligence echocardiography company). Dr Raj Makkar has received research grants from Edwards Lifesciences, Abbott, Medtronic, and Boston Scientific; has served as national principal investigator for Portico (Abbott) and Acurate (Boston Scientific) US investigation device exemption trials; has received personal proctoring fees from Edwards Lifesciences; and has received travel support from Edwards Lifesciences, Abbott, and Boston Scientific. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

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Graphical abstract

Figure 1

Figure 1

Computed Tomography Analysis of Tricuspid Valve Annulus

Figure 2

Figure 2

Defibrillator Lead Traversing the Tricuspid Annulus

References

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